Typical Testing Data/Standard Curve (for reference only)
Rat Alpha-actinin-4 ELISA Kit | Actn4 elisa kit
Rat Alpha-actinin-4 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
alpha-actinin cytoskeletal protein that anchors various actin-containing microfilaments to cellular structures; anchors V myosins to cellular structures via the RING finger-containing protein BERP [RGD, Feb 2006]
Uniprot Description
ACTN4: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Defects in ACTN4 are the cause of focal segmental glomerulosclerosis type 1 (FSGS1). A renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and edema. Renal insufficiency often progresses to end-stage renal disease, a highly morbid state requiring either dialysis therapy or kidney transplantation. Belongs to the alpha-actinin family.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Cellular Component: actin cytoskeleton; brush border; cortical cytoskeleton; cytoplasm; cytosol; extracellular space; focal adhesion; intercellular junction; intracellular; neuron projection; nucleus; perinuclear region of cytoplasm; protein complex; pseudopodium; ribonucleoprotein complex; stress fiber; Z disc
Molecular Function: actin filament binding; calcium ion binding; chromatin DNA binding; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; nucleoside binding; protein binding; protein complex binding; protein homodimerization activity; protein N-terminus binding; retinoic acid receptor binding
Biological Process: actin filament bundle formation; negative regulation of cell motility; positive regulation of cell migration; positive regulation of cell motility; positive regulation of pinocytosis; protein transport; regulation of apoptosis; response to hypoxia; retinoic acid receptor signaling pathway; vesicle transport along actin filament
Research Articles on Actn4
Similar Products
Product Notes
The Rat Actn4 actn4 (Catalog #AAA289366) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289366 ELISA Kit recognizes Rat Actn4. It is sometimes possible for the material contained within the vial of "Alpha-actinin-4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
