Rabbit anti-Human CD2BP2 Polyclonal Antibody | anti-CD2BP2 antibody

CD2BP2 Polyclonal Antibody

Cat. Num. AAA2565402

• Gene Names: CD2BP2; LIN1; Snu40; FWP010; U5-52K; PPP1R59
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity purification
• Synonyms: CD2BP2; Polyclonal Antibody; CD2BP2 Polyclonal Antibody; FWP010; LIN1; PPP1R59; Snu40; U5-52K; anti-CD2BP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 1mg/mL (varies by lot)

• Applicable Applications for anti-CD2BP2 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant fusion protein of human CD2BP2 (NP_0061011)
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines using CD2BP2 Polyclonal Antibody at dilution of 1:1000.)

Related Product Information for anti-CD2BP2 antibody

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Product Categories/Family for anti-CD2BP2 antibody

Immunology; Polyclonal Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 343887347
• NCBI GeneID: 10421
• NCBI Accession #: NP_001230575.1
• NCBI GenBank Nucleotide #: NM_001243646.1
• UniProt Accession #: O95400; Q9ULP2; B2RDX2
• Molecular Weight: 37,646 Da
• NCBI Official Full Name: CD2 antigen cytoplasmic tail-binding protein 2
• NCBI Official Synonym Full Names: CD2 (cytoplasmic tail) binding protein 2
• NCBI Official Symbol: CD2BP2
• NCBI Official Synonym Symbols: LIN1; Snu40; FWP010; U5-52K; PPP1R59
• NCBI Protein Information: CD2 antigen cytoplasmic tail-binding protein 2; U5 snRNP 52K protein; CD2 cytoplasmic domain-binding protein 2; protein phosphatase 1, regulatory subunit 59; CD2 antigen (cytoplasmic tail) binding protein 2
• UniProt Protein Name: CD2 antigen cytoplasmic tail-binding protein 2
• Protein Family: CD2 antigen cytoplasmic tail-binding protein
• UniProt Gene Name: CD2BP2
• UniProt Synonym Gene Names: KIAA1178; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; U5-52K
• UniProt Entry Name: CD2B2_HUMAN

NCBI Description

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]

Uniprot Description

CD2BP2: Binds the cytoplasmic domain of CD2 through the GYF domain.

Protein type: RNA processing; Spliceosome; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleoplasm; U4/U6 x U5 tri-snRNP complex; snRNP U5; cytoplasm; nuclear speck; nucleus

Molecular Function: ribonucleoprotein binding; protein binding

Biological Process: assembly of spliceosomal tri-snRNP; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression