Syntaxin 7 Recombinant Protein | STX7 recombinant protein

Syntaxin 7 Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121767

• Purity: >95% as determined by SDS-PAGE
• Synonyms: Syntaxin 7; Syntaxin 7 Protein; Human; Recombinant (His Tag); Human STX7/Syntaxin 7 Protein (His Tag); syntaxin 7; STX7 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Ser2-Leu238

• Species: Human
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: His
• Tag: N-His
• Protein Construction: A DNA sequence encoding the human STX7 (O15400-1)(Ser2-Leu238) was expressed with an N-terminal polyhistidine tag.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 20532414
• NCBI GeneID: 8417
• UniProt Accession #: O15400; Q5SZW2; Q96ES9; E1P579
• Molecular Weight: 261
• NCBI Official Full Name: Syntaxin-7
• NCBI Official Synonym Full Names: syntaxin 7
• NCBI Official Symbol: STX7
• NCBI Protein Information: syntaxin-7
• UniProt Protein Name: Syntaxin-7
• Protein Family: Syntaxin
• UniProt Gene Name: STX7
• UniProt Entry Name: STX7_HUMAN

Uniprot Description

STX7: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. Belongs to the syntaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q23.1

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; lysosome; early endosome; integral to membrane; immunological synapse; endomembrane system; SNARE complex; azurophil granule; recycling endosome; endocytic vesicle; perinuclear region of cytoplasm; early endosome membrane; late endosome; plasma membrane; vesicle; endosome

Molecular Function: SNAP receptor activity; SNARE binding; chloride channel inhibitor activity; syntaxin binding

Biological Process: vesicle fusion; intracellular protein transport; organelle localization; vesicle docking; positive regulation of T cell mediated cytotoxicity