SDS-Page
beta-Galactoside alpha-2,6-Sialyltransferase 1 Recombinant Protein | ST6GAL1 recombinant protein
Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1 Protein
Gene Names
ST6GAL1; ST6N; SIAT1; ST6GalI
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
beta-Galactoside alpha-2; 6-Sialyltransferase 1; Recombinant Human beta-Galactoside alpha-2; 6-Sialyltransferase 1 Protein; Beta-Galactoside Alpha-2; Alpha 2; 6-ST 1; B-Cell Antigen CD75; CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2; ST6Gal I; ST6GalI; Sialyltransferase 1; ST6GAL1; SIAT1; ST6GAL1 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Sequence Length
406
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fragment
Lys27-Cys406
Fusion Tag
C-6His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Please minimize freeze-thaw cycles.
SDS-Page
SDS-Page
Related Product Information for ST6GAL1 recombinant protein
Protein Construction: Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1 is produced by our Mammalian expression system and the target gene encoding Lys27-Cys406 is expressed with a 6His tag at the C-terminus.
Background: The ST6GAL1 gene encodes beta-Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galbeta1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
Background: The ST6GAL1 gene encodes beta-Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galbeta1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 44.6kDa
Actual Protein Molecular Mass: 41-48kDa
Actual Protein Molecular Mass: 41-48kDa
NCBI Official Full Name
beta-galactoside alpha-2,6-sialyltransferase 1 isoform a
NCBI Official Synonym Full Names
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
NCBI Official Symbol
ST6GAL1
NCBI Official Synonym Symbols
ST6N; SIAT1; ST6GalI
NCBI Protein Information
beta-galactoside alpha-2,6-sialyltransferase 1
UniProt Protein Name
Beta-galactoside alpha-2,6-sialyltransferase 1
Protein Family
UniProt Gene Name
ST6GAL1
UniProt Synonym Gene Names
SIAT1; Alpha 2,6-ST 1; ST6GalI
NCBI Description
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
Uniprot Description
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.
Research Articles on ST6GAL1
Similar Products
Product Notes
The ST6GAL1 st6gal1 (Catalog #AAA2556664) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "beta-Galactoside alpha-2,6-Sialyltransferase 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
