SDS-PAGE
ST6GAL1 / CD75 recombinant protein
Recombinant Mouse ST6GAL1 / CD75 Protein (His tag)
SDS-PAGE
SDS-PAGE
Description: A DNA sequence encoding the extracellular domain of mouse ST6GAL1 (NP_666045.1) (Lys 27-Cys 403) was fused with a polyhistidine tag at the N-terminus.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Nov 2011]
Uniprot Description
SIAT1: a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. Is normally found in the trans cisternae of the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found.
Protein type: EC 2.4.99.1; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 16 B1|16 14.03 cM
Cellular Component: endoplasmic reticulum; Golgi medial cisterna; Golgi trans cisterna
Molecular Function: beta-galactoside alpha-2,6-sialyltransferase activity; sialyltransferase activity
Biological Process: N-acetylneuraminate metabolic process; negative regulation of chemotaxis; oligosaccharide metabolic process; positive regulation of mononuclear cell proliferation; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine
Research Articles on ST6GAL1 / CD75
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Product Notes
The ST6GAL1 / CD75 st6gal1 (Catalog #AAA2546808) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse ST6GAL1 comprises 396 amino acids and predicts a molecular mass of 45.9 kDa. The apparent molecular mass of mouse ST6GAL1 is approximately 50-55 kDa in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the ST6GAL1 / CD75 st6gal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ST6GAL1 / CD75, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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