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Immunohistochemistry (IHC) (Anti-CD75 / ST6GAL1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)

Rabbit anti-Human CD75 / ST6GAL1 Polyclonal Antibody | anti-CD75 / ST6GAL1 antibody

Anti-CD75 / ST6GAL1 Antibody (aa178-206) IHC-plus

Gene Names
ST6GAL1; ST6N; SIAT1; ST6GalI
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity purified
Synonyms
CD75 / ST6GAL1; Polyclonal Antibody; Anti-CD75 / ST6GAL1 Antibody (aa178-206) IHC-plus; Rabbit Polyclonal to Human CD75 / ST6GAL1; Human CD75 / ST6GAL1; Alpha 2; 6-ST 1; Sialyltransferase 1; SIAT1; ST6Gal I; ST6GalI; ST6N; B-cell antigen CD75; anti-CD75 / ST6GAL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human CD75 / ST6GAL1
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
406
Applicable Applications for anti-CD75 / ST6GAL1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P (1:75)
WB (1:1000)
Immunogen
CD75 / ST6GAL1 antibody was raised against kLH-conjugated synthetic peptide from internal region of human ST6GAL1.
Immunogen Description
KLH-conjugated synthetic peptide from internal region of human ST6GAL1.
Immunogen Type
Synthetic peptide
Antigen Modification
aa178-206
Target Species
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Anti-CD75 / ST6GAL1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)

Immunohistochemistry (IHC) (Anti-CD75 / ST6GAL1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)

Western Blot (WB)

(ST6GAL1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The ST6GAL1 antibody detected the ST6GAL1 protein (arrow).)

Western Blot (WB) (ST6GAL1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The ST6GAL1 antibody detected the ST6GAL1 protein (arrow).)
Related Product Information for anti-CD75 / ST6GAL1 antibody
ST6GAL1 Antibody, Alpha 2,6-ST 1 Antibody, Sialyltransferase 1 Antibody, SIAT1 Antibody, ST6Gal I Antibody, ST6GalI Antibody, ST6N Antibody, B-cell antigen CD75 Antibody, CD75 Antibody Description: CD75 / ST6GAL1 is a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,764 Da
NCBI Official Full Name
beta-galactoside alpha-2,6-sialyltransferase 1 isoform a
NCBI Official Synonym Full Names
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
NCBI Official Symbol
ST6GAL1
NCBI Official Synonym Symbols
ST6N; SIAT1; ST6GalI
NCBI Protein Information
beta-galactoside alpha-2,6-sialyltransferase 1
UniProt Protein Name
Beta-galactoside alpha-2,6-sialyltransferase 1
UniProt Gene Name
ST6GAL1
UniProt Synonym Gene Names
SIAT1; Alpha 2,6-ST 1; ST6GalI
UniProt Entry Name
SIAT1_HUMAN

NCBI Description

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009]

Uniprot Description

SIAT1: a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. Is normally found in the trans cisternae of the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found.

Protein type: Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; EC 2.4.99.1; Transferase

Chromosomal Location of Human Ortholog: 3q27.3

Cellular Component: endoplasmic reticulum; Golgi medial cisterna; Golgi membrane; Golgi trans cisterna; integral to Golgi membrane

Molecular Function: beta-galactoside alpha-2,6-sialyltransferase activity; protein binding; sialyltransferase activity

Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; humoral immune response; N-acetylneuraminate metabolic process; negative regulation of chemotaxis; O-glycan processing; oligosaccharide metabolic process; positive regulation of mononuclear cell proliferation; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; protein amino acid O-linked glycosylation; response to ethanol

Research Articles on CD75 / ST6GAL1

Similar Products

Product Notes

The CD75 / ST6GAL1 st6gal1 (Catalog #AAA249517) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD75 / ST6GAL1 Antibody (aa178-206) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD75 / ST6GAL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:75) WB (1:1000). Researchers should empirically determine the suitability of the CD75 / ST6GAL1 st6gal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD75 / ST6GAL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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