Related Product Information for SP-D elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate SFTPD in samples. An antibody specific for SFTPD has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySFTPD present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SFTPD is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SFTPD bound in the initial step. The color development is stopped and the intensity of the color is measured.
Uniprot Description
SFTPD: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 16p14
Cellular Component: collagen; cytoplasm; cytoplasmic vesicle; extracellular space; multivesicular body; proteinaceous extracellular matrix; rough endoplasmic reticulum
Molecular Function: identical protein binding; lipopolysaccharide binding; monosaccharide binding
Biological Process: alveolus development; induction of bacterial agglutination; innate immune response; negative regulation by host of symbiont molecular function; negative regulation of interleukin-2 production; negative regulation of phagocytosis; negative regulation of T cell proliferation; opsonization; positive regulation of phagocytosis; regulation of liquid surface tension; respiratory gaseous exchange; response to corticosteroid stimulus; response to glucocorticoid stimulus; response to hyperoxia; surfactant homeostasis
Product Notes
The Rat SP-D sftpd (Catalog #
AAA280963) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA280963 ELISA Kit recognizes Rat SP-D.
It is sometimes possible for the material contained within the vial of
"Pulmonary Surfactant-associated protein D, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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