SDS-Page
(15% SDS PAGE using S1014-70Q, 3ug.)
SNAP 25 Recombinant Protein | Snap25 recombinant protein
SNAP 25, Recombinant, Human (SNAP25, Synaptosomal-associated Protein 25)
~90% by SDS PAGE
~90% by SDS PAGE
LADESLESTR RMLQLVEESK
DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL
RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG
SDS-Page
(15% SDS PAGE using S1014-70Q, 3ug.)
SDS-Page
(15% SDS PAGE using S1014-70Q, 3ug.)
NCBI and Uniprot Product Information
NCBI Description
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein. It is essential for regulated exocytosis in neuronal cells. Alternative transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2012]
Uniprot Description
SNAP-25: a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Part of the SNARE core complex containing SNAP25, VAMP2 and syntaxin 1A. Associates with proteins involved in vesicle docking and membrane fusion. Two alternatively spliced isoforms have been described.
Protein type: Vesicle
Cellular Component: voltage-gated potassium channel complex; neuron projection; cell; terminal button; intracellular organelle; trans-Golgi network; cytosol; lipid raft; actin cytoskeleton; SNARE complex; growth cone; membrane; cell soma; axon; lamellipodium; perinuclear region of cytoplasm; cytoplasm; plasma membrane; synapse; cell junction; myelin sheath; endosome; vesicle; filopodium
Molecular Function: protein domain specific binding; SNAP receptor activity; SNARE binding; voltage-gated potassium channel activity; protein binding; myosin binding; syntaxin-1 binding; protein N-terminus binding; calcium-dependent protein binding
Biological Process: exocytosis; neurotransmitter secretion; calcium ion-dependent exocytosis of neurotransmitter; positive regulation of hormone secretion; positive regulation of insulin secretion; endosome transport; sleep; synaptic vesicle fusion to presynaptic membrane; growth hormone secretion; axonogenesis; long-term memory; regulation of synaptogenesis; synaptic vesicle priming
Research Articles on Snap25
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Product Notes
The Snap25 snap25 (Catalog #AAA636366) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MAEDADMRNE LEEMQRRADQ LADESL ESTR RMLQLVEESK DAGIRT LVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALD MGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG. It is sometimes possible for the material contained within the vial of "SNAP 25, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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