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SDS-Page

SMOC1 recombinant protein

SMOC1 Protein, Human, Recombinant (His Tag)

Gene Names
SMOC1; OAS
Purity
>92% as determined by SDS-PAGE
Synonyms
SMOC1; SMOC1 Protein; Human; Recombinant (His Tag); Human SMOC1 Protein (His Tag); OAS Protein; SPARC related modular calcium binding 1; SMOC1 recombinant protein
Ordering
For Research Use Only!
Host
HEK293 Cells
Purity/Purification
>92% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Val435
Species
Human
Endotoxin
<1.0EU per ug of the protein as determined by the LAL method
Predicted N Terminal
His 27
Tag
C-His
Protein Construction
A DNA sequence encoding the human SMOC1 isoform 1 (NP_001030024.1)(Met 1-Val 435) was expressed, fused with a polyhistidine tag at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.

SDS-Page

SDS-Page
Related Product Information for SMOC1 recombinant protein
Background: SPARC-related modular calcium-binding protein 1, also known as secreted modular calcium-binding protein 1 and SMOC1, is a member of the SPARC family. SMOC1 is widely expressed in many tissues with a strongest signal in ovary. It contains two EF-hand domains, one Kazal-like domain and two thyroglobulin type-1 domains. Extracellular matrix proteins have been implicated in the regulation of osteoblast differentiation of bone marrow-derived mesenchymal stem cells (BMSCs) through paracrine or autocrine mechanisms. SMOC1 is a regulator of osteoblast differentiation of BMSCs. SMOC1 is highly expressed and secreted in BMSCs stimulated with osteogenic medium (OSM). SMOC1 and SMOC2 are matricellular proteins thought to influence growth factor signaling, migration, proliferation, and angiogenesis. SMOC1 and SMOC2 may mediate intercellular signaling and cell type-specific differentiation during gonad and reproductive tract development.
Product Categories/Family for SMOC1 recombinant protein
References
Vannahme C. et al., 2002 J. Biol. Chem. 277:37977-86. Pazin,D.E. et al., 2009, Dev Dyn. 238 (11): 2877-90. Choi,Y.A. et al., 2010, J Proteome Res. 9 (6):2946-56.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,163 Da
NCBI Official Full Name
SPARC-related modular calcium-binding protein 1 isoform 1
NCBI Official Synonym Full Names
SPARC related modular calcium binding 1
NCBI Official Symbol
SMOC1
NCBI Official Synonym Symbols
OAS
NCBI Protein Information
SPARC-related modular calcium-binding protein 1; secreted modular calcium-binding protein 1
UniProt Protein Name
SPARC-related modular calcium-binding protein 1
UniProt Gene Name
SMOC1
UniProt Synonym Gene Names
SMOC-1
UniProt Entry Name
SMOC1_HUMAN

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Product Notes

The SMOC1 smoc1 (Catalog #AAA8121055) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Val43 5. It is sometimes possible for the material contained within the vial of "SMOC1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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