Western Blot (WB)
(Western Blot detection against Immunogen (34.03kD).)
Mouse anti-Human SMOC1 Monoclonal Antibody | anti-SMOC1 antibody
SMOC1 (SPARC-Related Modular Calcium-Binding Protein 1, Secreted Modular Calcium-Binding Protein 1, SMOC-1)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: Immunofluorescence: 10ug/ml
Western Blot (WB)
(Western Blot detection against Immunogen (34.03kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (34.03kD).)
Western Blot (WB)
(SMOC1 monoclonal antibody, Western Blot analysis of SMOC1 expression in A-431.)
Western Blot (WB)
(SMOC1 monoclonal antibody, Western Blot analysis of SMOC1 expression in A-431.)
Western Blot (WB)
(Western Blot analysis of SMOC1 expression in transfected 293T cell line by SMOC1 monoclonal antibody.|Lane 1: SMOC1 transfected lysate (48.3kD).|Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of SMOC1 expression in transfected 293T cell line by SMOC1 monoclonal antibody.|Lane 1: SMOC1 transfected lysate (48.3kD).|Lane 2: Non-transfected lysate.)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to SMOC1 on A-431 cell. [antibody concentration 10ug/ml].)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to SMOC1 on A-431 cell. [antibody concentration 10ug/ml].)
Testing Data
(Detection limit for recombinant GST tagged SMOC1 is ~1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged SMOC1 is ~1ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Uniprot Description
Function: Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation. Ref.6 Ref.7 Ref.8
Subcellular location: Secreted › extracellular space › extracellular matrix › basement membrane. Note: In or around the basement membrane. Ref.1 Ref.6
Tissue specificity: Widely expressed in many tissues with a strongest signal in ovary. No expression in spleen. Ref.1
Post-translational modification: Glycosylated. Ref.1
Involvement in disease: Ophthalmoacromelic syndrome (OAS) [MIM:206920]: A rare disorder presenting with ocular anomalies, ranging from mild microphthalmia to true anophthalmia, and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and oligodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.7 Ref.8 Ref.9 Ref.10
Sequence similarities: Contains 2 EF-hand domains.Contains 1 Kazal-like domain.Contains 2 thyroglobulin type-1 domains.
Research Articles on SMOC1
Similar Products
Product Notes
The SMOC1 smoc1 (Catalog #AAA648224) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SMOC1 (SPARC-Related Modular Calcium-Binding Protein 1, Secreted Modular Calcium-Binding Protein 1, SMOC-1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SMOC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF). Suitable for use in Immunofluorescence, ELISA and Western Blot. Dilution: Immunofluorescence: 10ug/ml. Researchers should empirically determine the suitability of the SMOC1 smoc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SVQNKTPVCS GSVTDKPLSQ GNSGRKDDGS KPTPTMETQP VFDGDEITAP TLWIKHLVIK DSKLNNTNIR NS. It is sometimes possible for the material contained within the vial of "SMOC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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