Western Blot (WB)
(Western blotAll lanes: SMOC1 antibody at 14 ug/ml+ Mouse skeletal muscle tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 48 kDaObserved band size: 48 kDa)
Rabbit anti-Human, Mouse SMOC1 Polyclonal Antibody | anti-SMOC1 antibody
SMOC1 Antibody
IHC: 1:20-1:200
IF: 1:50-1:200
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Western Blot (WB)
(Western blotAll lanes: SMOC1 antibody at 14 ug/ml+ Mouse skeletal muscle tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 48 kDaObserved band size: 48 kDa)
Western Blot (WB)
(Western blotAll lanes: SMOC1 antibody at 14 ug/ml+ Mouse skeletal muscle tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 48 kDaObserved band size: 48 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045999 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045999 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7045999 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7045999 at dilution 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG-2 cells using MBS7045999 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG-2 cells using MBS7045999 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Uniprot Description
SMOC1: Plays essential roles in both eye and limb development. Probale regulator of osteoblast differentiation. Defects in SMOC1 are the cause of ophthalmoacromelic syndrome (OAS). A rare disorder presenting with anophthalmia or microphthalmia and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and olygodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 14q24.2
Molecular Function: protein binding
Biological Process: eye development; limb development; regulation of osteoblast differentiation
Disease: Microphthalmia With Limb Anomalies
Research Articles on SMOC1
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Product Notes
The SMOC1 smoc1 (Catalog #AAA7045999) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMOC1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SMOC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:1000-1:5000 IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the SMOC1 smoc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMOC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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