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64 results for "PDGFR inhibitor" - showing 1-50
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Pancreas stained with AKT1 Mouse Monoclonal Antibody (AKT1/2491).)
AKT1, Monoclonal Antibody (Cat# AAA439937)
Full Name
AKT1 (Proto-Oncogene)
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human. Others not known
Applications
IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Pancreas stained with AKT1 Mouse Monoclonal Antibody (AKT1/2552).)
AKT1, Monoclonal Antibody (Cat# AAA439938)
Full Name
AKT1 (Proto-Oncogene)
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human. Others not known
Applications
IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Chemical Structure
Foretinib (GSK1363089, XL880), Inhibitor (Cat# AAA384812)
Full Name
Foretinib (GSK1363089, XL880)
Purity
>98%
Pricing
$125/5 mg | $200/25 mg | $300/50 mg | $465/100 mg | $150/1 mL (in DMSO) | $2,050/5x100 mg
Molecular Structure
STO-609, Inhibitor (Cat# AAA515066)
Full Name
STO-609
Purity
>98% (TLC); NMR (Conforms)
Pricing
$215/5 mg | $445/25 mg | $1,780/5x25 mg
Pazopanib HCl, Inhibitor (Cat# AAA579455)
Full Name
Pazopanib HCl (GW786034 HCl)
Purity
98.0%
Pricing
$200/10 mg | $230/25 mg | $250/50 mg | $275/100 mg | $490/500 mg | $360/200 mg | $200/1 mL (in DMSO) | $1,940/5x500 mg
Structure
Palbociclib, Inhibitor (Cat# AAA577445)
Full Name
Palbociclib
Purity
99.2%
Pricing
$200/5 mg | $210/10 mg | $235/50 mg | $255/100 mg | $275/200 mg | $975/5x200 mg
Molecular Structure
Necrostatin-1, Inhibitor (Cat# AAA515041)
Full Name
Necrostatin-1
Purity
>98% (TLC: 1:9, CH3OH:CH2Cl2; Rf=0.6); NMR (Conforms)
Pricing
$225/10 mg | $415/50 mg | $1,645/5x50 mg
Molecular Structure
Gefitinib, Inhibitor (Cat# AAA515056)
Full Name
Gefitinib
Purity
>98% (TLC); NMR conforms
Pricing
$190/50 mg | $350/250 mg | $1,345/5x250 mg
Chemical Structure
(Chemical structure of SU 4312 (SIH-481), a VEGFR / PDGFR kinase inhibitor. CAS #: 5812-07-7. Molecular Formula: C17H16N2O. Molecular Weight: 264.3 g/mol.)
SU 4312, Small Molecule (Cat# AAA808180)
Full Name
SU 4312
Purity
>=98% (HPLC)
Pricing
$205/5 mg | $430/25 mg | $1,695/5x25 mg | $700/5x5 mg
Testing Data
(PP121 is a multitargeted dual receptor tyrosine kinases inhibitor with IC50 of 0.052, 1.4, 0.15, 1.1, 0.06, 0.01and 0.002 uM for p110alpha, p110beta, p110delta, p110gamma, DNA-PK, mTOR and PDGFR, respectively. PP121 also inhibits Abl, Hck, Src,Src(T338I), VEGFR2, EGFR EphB4 with IC50 of 0.018, 0.008, 0.014, 0.22, 0.012, 0.26, 0.19 uM, respectively. PP121 exhibits no significant effect on receptor serine/threonine kinases (RSTKs). PP121 blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor. PP121 achieves its dual potency by targeting a residue (Glu310 in Src) that has been structurally conserved between kinase families. PP121 potently and dose-dependently blocked the phosphorylation of Akt, p70S6K and S6 in these cells. [1])
Structure
Imatinib, Inhibitor (Cat# AAA578793)
Full Name
Imatinib (STI571)
Purity
99.94%
Pricing
$165/10 mg | $185/50 mg | $185/100 mg | $205/250 mg | $655/5x250 mg
Structure
Mubritinib, Inhibitor (Cat# AAA578692)
Full Name
Mubritinib (TAK 165)
Purity
99.57%
Pricing
$205/10 mg | $240/25 mg | $300/50 mg | $430/100 mg | $690/200 mg | $195/1 mL (in DMSO) | $2,845/5x200 mg
Structure
CP-673451, Inhibitor (Cat# AAA578664)
Full Name
CP-673451
Purity
99.9%
Pricing
$200/1 mg | $210/2 mg | $250/5 mg | $335/10 mg | $510/25 mg | $750/50 mg | $1,165/100 mg | $260/1 mL (in DMSO) | $4,950/5x100 mg
Chemical Structure
(Chemical structure of Sunitinib malate (SIH-482), a VEGFR, PDGFR kinase inhibitor. CAS #: 557795-19-4. Molecular Formula: C22H27FN4O2. Molecular Weight: 398.5 g/mol.)
Sunitinib malate, Small Molecule (Cat# AAA808181)
Full Name
Sunitinib malate
Purity
>=99%
Pricing
$215/5 mg | $515/25 mg | $2,110/5x25 mg | $755/5x5 mg
JI-101, Inhibitor (Cat# AAA579606)
Full Name
JI-101
Purity
99.4%
Pricing
$210/2 mg | $250/5 mg | $300/10 mg | $455/25 mg | $750/50 mg | $1,150/100 mg | $250/1 mL (in DMSO) | $4,900/5x100 mg
Structure
Tyrphostin AG 1296, Inhibitor (Cat# AAA579244)
Full Name
Tyrphostin AG 1296
Purity
99.7%
Pricing
$210/2 mg | $250/5 mg | $290/10 mg | $390/25 mg | $530/50 mg | $850/100 mg | $255/1 mL (in DMSO) | $3,565/5x100 mg
Chemical Structure
(Chemical structure of AG1296 (SIH-426), a PDGFR kinase inhibitor. CAS #: 146535-11-7. Molecular Formula: C16H14N2O2. Molecular Weight: 266.3 g/mol.)
AG1296, Small Molecule (Cat# AAA808128)
Full Name
AG1296
Purity
>=98% (TLC)
Pricing
$220/5 mg | $540/25 mg | $2,195/5x25 mg | $770/5x5 mg
CP-724714, Inhibitor (Cat# AAA579919)
Full Name
CP-724714
Purity
98.82%
Pricing
$205/2 mg | $235/5 mg | $295/10 mg | $430/25 mg | $595/50 mg | $835/100 mg | $235/1 mL (in DMSO) | $3,495/5x100 mg
NSC 86429, Inhibitor (Cat# AAA579686)
Full Name
NSC 86429
Purity
99.0%
Pricing
$200/2 mg | $230/5 mg | $275/10 mg | $375/25 mg | $515/50 mg | $715/100 mg | $2,955/5x100 mg
Chemical Structure
Flumatinib, Inhibitor (Cat# AAA5750459)
Full Name
Flumatinib
Purity
100.0%
Pricing
$210/5 mg | $225/10 mg | $265/25 mg | $300/50 mg | $400/100 mg | $545/200 mg | $225/1 mL (in DMSO) | $2,175/5x200 mg
Structure
Structure
SKLB 610, Inhibitor (Cat# AAA3600442)
Full Name
SKLB 610
Purity
>98% (HPLC)
Pricing
$205/5 mg | $250/10 mg | $345/25 mg | $470/50 mg | $615/100 mg | $785/200 mg | $3,225/5x200 mg
Structure
Axitinib, Inhibitor (Cat# AAA3604038)
Full Name
Axitinib
Purity
>98% (HPLC)
Pricing
$185/25 mg | $190/50 mg | $205/100 mg | $230/200 mg | $750/5x200 mg
Structure
CHIR-124, Inhibitor (Cat# AAA3604392)
Full Name
CHIR-124
Purity
>98% (HPLC)
Pricing
$190/2 mg | $225/5 mg | $265/10 mg | $360/25 mg | $555/50 mg | $760/100 mg | $3,145/5x100 mg
Structure
Tyrphostin AG 879, Inhibitor (Cat# AAA3607314)
Full Name
Tyrphostin AG 879
Purity
>98% (HPLC)
Pricing
$190/5 mg | $215/10 mg | $310/25 mg | $660/100 mg | $2,680/5x100 mg
Structure
PP 242, Inhibitor (Cat# AAA3600346)
Full Name
PP 242
Purity
>98% (HPLC)
Pricing
$200/5 mg | $210/10 mg | $245/25 mg | $260/50 mg | $330/100 mg | $415/200 mg | $1,590/5x200 mg
Structure
Pazopanib hydrochloride, Inhibitor (Cat# AAA3605405)
Full Name
Pazopanib hydrochloride
Purity
>98% (HPLC)
Pricing
$190/10 mg | $225/25 mg | $265/100 mg | $455/500 mg | $340/200 mg | $1,760/5x500 mg
Flumatinib mesylate, Inhibitor (Cat# AAA3611094)
Full Name
Flumatinib mesylate
Purity
>98% (HPLC)
Pricing
$190/5 mg | $570/5x5 mg
Structure
Structure
Toceranib, Inhibitor (Cat# AAA5754056)
Full Name
Toceranib
Purity
98.00%
Pricing
$230/10 mg | $355/50 mg | $1,315/5x50 mg
Structure
Mubritinib, Inhibitor (Cat# AAA3608472)
Full Name
Mubritinib
Purity
>98% (HPLC)
Pricing
$235/25 mg | $290/50 mg | $395/100 mg | $635/200 mg | $2,575/5x200 mg
Tyrphostin AG1433, Inhibitor (Cat# AAA5754076)
Full Name
Tyrphostin AG1433
Purity
98.00%
Pricing
$275/5 mg | $345/10 mg | $685/50 mg | $1,020/100 mg | $285/1mL*10mM (in DMSO) | $4,310/5x100 mg
Structure
5Z-7-Oxozeaenol, Inhibitor (Cat# AAA5754443)
Full Name
5Z-7-Oxozeaenol
Purity
98.00%
Pricing
$265/1 mg | $600/5 mg | $2,415/5x5 mg
Structure
AG 1295, Inhibitor (Cat# AAA5754484)
Full Name
AG 1295
Purity
98.00%
Pricing
$215/5 mg | $260/10 mg | $470/50 mg | $225/1 mL (in DMSO) | $1,840/5x50 mg
AC710, Inhibitor (Cat# AAA5764487)
Full Name
AC710
Purity
98.00%
Pricing
$200/1 mg | $280/5 mg | $335/10 mg | $590/25 mg | $960/50 mg | $1,580/100 mg | $305/1 mL (in DMSO) | $6,825/5x100 mg
Regorafenib monohydrate, Inhibitor (Cat# AAA5755754)
Full Name
Regorafenib monohydrate
Purity
98.00%
Pricing
$195/5 mg | $235/50 mg | $275/100 mg | $340/200 mg | $205/1 mL (in DMSO) | $1,260/5x200 mg
Chemical Structure
TAK-593, Inhibitor (Cat# AAA387907)
Full Name
TAK-593
Purity
>98%
Pricing
$230/5 mg | $340/10 mg | $625/25 mg | $2,760/5x25 mg
Structure
Avapritinib, Inhibitor (Cat# AAA5751569)
Full Name
Avapritinib
Purity
96.59%
Pricing
$215/1 mg | $250/2 mg | $330/5 mg | $435/10 mg | $670/25 mg | $905/50 mg | $1,295/100 mg | $350/1 mL (in DMSO) | $5,565/5x100 mg
Structure
PDGFRalpha kinase 1, Inhibitor (Cat# AAA5753656)
Full Name
PDGFRalpha kinase inhibitor 1
Purity
98.00%
Pricing
$425/5 mg | $600/10 mg | $970/25 mg | $1,525/50 mg | $2,245/100 mg | $515/1mL*10mM (in DMSO) | $9,830/5x100 mg
Structure
Sunitinib, Inhibitor (Cat# AAA3605026)
Full Name
Sunitinib
Purity
>98% (HPLC)
Pricing
$200/100 mg | $215/200 mg | $695/5x200 mg
740 Y-P(TFA), Inhibitor (Cat# AAA5764261)
Full Name
740 Y-P(TFA)
Purity
98.89%
Pricing
$240/1 mg | $380/5 mg | $485/10 mg | $720/25 mg | $1,040/50 mg | $1,485/100 mg | $6,410/5x100 mg
Structure
Tyrphostin 9, Inhibitor (Cat# AAA3607776)
Full Name
Tyrphostin 9
Purity
>98% (HPLC)
Pricing
$215/50 mg | $250/100 mg | $300/200 mg | $1,055/5x200 mg
Structure
JNJ-?10198409, Inhibitor (Cat# AAA5755023)
Full Name
JNJ-?10198409
Purity
98.00%
Pricing
$225/1 mg | $310/5 mg | $390/10 mg | $600/25 mg | $835/50 mg | $1,115/100 mg | $325/1 mL (in DMSO) | $4,750/5x100 mg
PD168393, Inhibitor (Cat# AAA3607403)
Full Name
PD168393
Purity
>98% (HPLC)
Pricing
$190/2 mg | $205/5 mg | $230/10 mg | $280/25 mg | $335/50 mg | $405/100 mg | $1,530/5x100 mg
Structure
Ripretinib, Inhibitor (Cat# AAA5759275)
Full Name
Ripretinib
Purity
98.00%
Pricing
$225/1 mg | $295/5 mg | $375/10 mg | $580/25 mg | $985/50 mg | $1,565/100 mg | $385/1 mL (in DMSO) | $6,770/5x100 mg
Structure
AG-1478, Inhibitor (Cat# AAA3602161)
Full Name
AG-1478
Purity
>98% (HPLC)
Pricing
$200/5 mg | $215/10 mg | $280/25 mg | $360/50 mg | $545/100 mg | $870/200 mg | $3,620/5x200 mg
Structure
Flumatinib mesylate, Inhibitor (Cat# AAA5758724)
Full Name
Flumatinib mesylate
Purity
99.82%
Pricing
$240/500 mg | $195/1 mL (in DMSO) | $810/5x500 mg
Structure
JI-101, Inhibitor (Cat# AAA3607645)
Full Name
JI-101
Purity
>98% (HPLC)
Pricing
$205/2 mg | $245/5 mg | $290/10 mg | $425/25 mg | $690/50 mg | $2,825/5x50 mg
Structure
PP58, Inhibitor (Cat# AAA5754366)
Full Name
PP58
Purity
98.00%
Pricing
$425/5 mg | $560/10 mg | $1,400/50 mg | $6,005/5x50 mg
Structure
Vorolanib, Inhibitor (Cat# AAA5759284)
Full Name
Vorolanib
Purity
98.00%
Pricing
$270/1 mg | $435/5 mg | $625/10 mg | $995/25 mg | $1,405/50 mg | $1,875/100 mg | $445/1 mL (in DMSO) | $8,180/5x100 mg
