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57 results for "uPA inhibitor" - showing 1-50


Activity Data (Figure. The binding activity of tPA with PAI1.Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator (tPA).Tissue plasminogen activators (tPA) are used to treat medical conditions related to blood clotting including embolic or thrombotic stroke, myocardial infarction, and pulmonary embolism. Besides, Plasminogen Activator Inhibitor 1 (PAI1) has been identified as an interactor of tPA, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse tPA and recombinant mouse PAI1. Briefly, tPA were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to PAI1-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-tPA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of tPA and PAI1 was shown in Figure 1, and this effect was in a dose dependent manner.)

Plasminogen Activator, Tissue (tPA), Active Protein (Cat# AAA2105096)

Full Name
Active Plasminogen Activator, Tissue (tPA)
Gene Names
Plat; tPA; AU020998; AW212668; D8Ertd2e
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$245/0.01 mg | $530/0.05 mg | $820/0.1 mg | $1,020/0.2 mg | $1,985/0.5 mg | $2,945/1 mg | $7,200/5 mg

PAI-1 (stable mutant form), Active Protein (Cat# AAA135665)

Full Name
Human PAI-1 (stable mutant form)
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
>95% by SDS-PAGE analysis
Pricing
$825/0.5 mg | $1,280/1 mg | $5,545/5x1 mg
SDS-Page (3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)

PAI-1, Active Protein (Cat# AAA203116)

Full Name
PAI-1, 24-402aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Applications
SDS-PAGE, Enzyme Activity
Purity
> 95% by SDS-PAGE
Pricing
$215/0.02 mg | $340/0.1 mg | $765/0.5 mg | $3,195/5x0.5 mg
SDS-Page (Recombinant Human Serpin E1 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.)

Serpin E1, Active Protein (Cat# AAA9139964)

Full Name
Recombinant Human Serpin E1 Protein
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
>95% by SDS-PAGE.
Pricing
$215/0.01 mg | $435/0.05 mg | $1,300/0.5 mg | $1,835/1 mg | $8,195/5x1 mg

Plasminogen Activator Inhibitor 1, Recombinant, Recombinant Protein (Cat# AAA319078)

Full Name
Mouse PAI-1, Recombinant
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
Mouse
Purity
>98% pure (SDS-PAGE). 80 + 5% active by uPA titration. Column chromatography
Pricing
$1,865/0.5 mg | $8,185/5x0.5 mg

PAI2, Active Protein (Cat# AAA539367)

Full Name
PAI2 protein
Gene Names
SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201
Applications
User optimized
Purity
> 95% pure
Pricing
$425/0.01 mg | $1,905/5x0.01 mg

Plasminogen Activator Inhibitor Type 1, inhibitory, Monoclonal Antibody (Cat# AAA609010)

Full Name
Plasminogen Activator Inhibitor Type 1, inhibitory (PAI-1)
Reactivity
Human, Mouse
Applications
EL/EIA, WB, IHC
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Pricing
$1,050/0.5 mg | $1,885/1 mg | $8,480/5x1 mg
Typical Testing Data/Standard Curve (for reference only)

PAI-1 uPA complex antigen assay, ELISA Kit (Cat# AAA135489)

Full Name
Human PAI-1 uPA complex antigen assay ELISA Kit
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
General
Pricing
$585/1 Kit | $2,140/5 Kits | $9,925/5x5 Kits

PAI1, Monoclonal Antibody (Cat# AAA530230)

Full Name
PAI1 antibody
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
Human PAL1
Applications
EIA, IHC
Pricing
$750/0.5 mg | $3,355/5x0.5 mg
Testing Data #1 (Formalin fixed human breast invasive ductal carcinoma stained with Rabbit anti human PAI-1 (MBS223369) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))

PAI-1, Polyclonal Antibody (Cat# AAA223369)

Full Name
RABBIT ANTI HUMAN PAI-1
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Applications
EIA, WB
Pricing
$610/0.1 mg | $2,595/5x0.1 mg

PAI1, Monoclonal Antibody (Cat# AAA530725)

Full Name
PAI1 antibody
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Applications
WB
Pricing
$290/0.1 mg | $1,305/5x0.1 mg

Plasminogen Activator Inhibitor Type 1, Inhibitory, Monoclonal Antibody (Cat# AAA632488)

Full Name
Plasminogen Activator Inhibitor Type 1, Inhibitory (PAI-1)
Reactivity
Human, Mouse
Applications
EL/EIA, WB, IHC
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Pricing
$1,885/1 mg | $8,480/5x1 mg

Glycosylated PAI-1, Native Protein (Cat# AAA135965)

Full Name
Glycosylated Rat PAI-1 (stable mutant)
Gene Names
Serpine1; Pai1; PAI1A; Planh; Pai1aa; RATPAI1A
Purity
>95% by SDS-PAGE analysis
Pricing
$1,090/0.5 mg | $1,675/1 mg | $7,320/5x1 mg

Glycosylated Mouse PAI-1 (stable mutant), Active Protein (Cat# AAA135766)

Full Name
Glycosylated Mouse PAI-1 (stable mutant)
Gene Names
Serpine1; PAI1; PAI-1; Planh1
Purity
>95% by SDS-PAGE analysis
Pricing
$1,090/0.5 mg | $1,675/1 mg | $7,320/5x1 mg

PAI1, Monoclonal Antibody (Cat# AAA530989)

Full Name
PAI1 antibody
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
Human PAL1
Applications
EIA
Pricing
$750/0.5 mg | $3,355/5x0.5 mg
Testing Data

PAI-1 NBD labeled at the reactive center loop, Active Protein (Cat# AAA135746)

Full Name
Human PAI-1 NBD labeled at the reactive center loop
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
>95% by SDS-PAGE analysis
Pricing
$825/0.5 mg | $1,445/1 mg | $6,280/5x1 mg

PAI1, Monoclonal Antibody (Cat# AAA530267)

Full Name
PAI1 antibody
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
Human PAL1
Applications
EIA
Pricing
$750/0.5 mg | $3,355/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, peptide annealed, Protein (Cat# AAA634919)

Full Name
Plasminogen Activator Inhibitor Type 1, peptide annealed, Human (PAI-1)
Purity
Highly Purified
>98% pure by SDS PAGE 95 (+/-) 5% active by uPA titration.
Acts as a substrate for plasminogen activators.
Pricing
$1,355/0.5 mg | $6,100/5x0.5 mg

PAI-1 uPA complex, Protein (Cat# AAA135648)

Full Name
Human PAI-1 uPA complex
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
>95% by SDS-PAGE analysis
Pricing
$455/0.1 mg | $3,045/1 mg

Plasminogen Activator Inhibitor Type 1, active wild type, Protein (Cat# AAA634675)

Full Name
Plasminogen Activator Inhibitor Type 1, Human, active wild type (PAI-1) (Biotin)
Purity
Highly Purified
98% by SDS PAGE 95 ± 5% active by uPA titration
Pricing
$1,345/0.5 mg | $6,050/5x0.5 mg

PAI-1 stable mutant NBD labeled at the reactive center loop, Active Protein (Cat# AAA135778)

Full Name
Human PAI-1 stable mutant NBD labeled at the reactive center loop
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
>95% by SDS-PAGE analysis
Pricing
$825/0.5 mg | $1,445/1 mg | $6,280/5x1 mg

Plasminogen Activator Inhibitor Type 1, 6X His Tag, Protein (Cat# AAA634767)

Full Name
Plasminogen Activator Inhibitor Type 1, 6X His Tag, Human (PAI-1)
Purity
Highly Purified
>99% pure by SDS PAGE 98 ±2% active by uPA titration.
Pricing
$1,355/0.5 mg | $6,100/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, wild type, Rat, Protein (Cat# AAA634485)

Full Name
Plasminogen Activator Inhibitor Type 1, wild type, Rat (PAI-1)
Purity
Purified
>98% pure by SDS PAGE 90±5% active by uPA titration.
Pricing
$1,330/0.5 mg | $5,980/5x0.5 mg

Urinary Trypsin Inhibitor Fragment, Peptide (Cat# AAA658852)

Full Name
Urinary Trypsin Inhibitor Fragment
Gene Names
PLAU; ATF; QPD; UPA; URK; u-PA; BDPLT5
Purity
Highly Purified
~95%. Purified by HPLC.
Pricing
$600/1 mg | $2,695/5x1 mg

Plasminogen Activator Inhibitor Type 1, wild type, Porcine, Protein (Cat# AAA634815)

Full Name
Plasminogen Activator Inhibitor Type 1, wild type, Porcine (PAI-1)
Purity
Highly Purified
>98% pure by SDS PAGE 90 (+/-) 5% active by uPA titration.
Pricing
$1,355/0.5 mg | $6,100/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, stable mutant, Protein (Cat# AAA634702)

Full Name
Plasminogen Activator Inhibitor Type 1, Human, stable mutant (PAI-1) (Biotin)
Purity
Highly Purified
~98% by SDS PAGE 95 (+/-) 5% active by uPA titration
Pricing
$1,345/0.5 mg | $6,050/5x0.5 mg

Plasminogen, Rabbit, Active Protein (Cat# AAA634309)

Full Name
Plasminogen, Rabbit
Purity
Purified
98% (SDS-PAGE)
Pricing
$870/1 mg | $3,910/5x1 mg

PAI1, Monoclonal Antibody (Cat# AAA838119)

Full Name
PAI1 antibody
Gene Names
SERPINE1; PAI1
Reactivity
Human
Applications
EIA, WB, IHC
Purity
PAI1 antibody was purified from cell culture supernatant by protein A/G chromatography
Pricing
$1,765/0.4 mL | $7,935/5x0.4 mL

Plasminogen Activator Inhibitor Type 1, Active Protein (Cat# AAA637507)

Full Name
Plasminogen Activator Inhibitor Type 1, Human, Recombinant (PAI 1)
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
Purified
~ 98%, as determined by SDS-PAGE gel electrophoresis.
Pricing
$775/0.05 mg | $3,470/5x0.05 mg

Plasminogen, Chicken, Active Protein (Cat# AAA634649)

Full Name
Plasminogen, Chicken
Purity
Purified
98% (SDS-PAGE)
Pricing
$720/1 mg | $3,235/5x1 mg

PAI-1, Protein (Cat# AAA480716)

Full Name
Human PAI-1 uPA Complex
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Pricing
$610/0.1 mg | $2,530/5x0.1 mg

Plasminogen Activator Inhibitor Type 1, stable mutant, Protein (Cat# AAA634957)

Full Name
Plasminogen Activator Inhibitor Type 1, Human, stable mutant (PAI-1)
Purity
Highly Purified
>98% pure by SDS PAGE 95 ± 5% active by uPA titration
Pricing
$1,345/0.5 mg | $6,050/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, wild type active, Murine, Active Protein (Cat# AAA634761)

Full Name
Plasminogen Activator Inhibitor Type 1, wild type active, Murine (PAI-1)
Purity
Purified
Purified (> 98% pure by SDS PAGE).
Pricing
$1,330/0.5 mg | $5,980/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, mutant, active wild type, Protein (Cat# AAA635245)

Full Name
Plasminogen Activator Inhibitor Type 1, Human, mutant, active wild type (PAI-1)
Purity
Highly Purified
>98% pure by SDS PAGE 95 (+/-) 5% active by uPA titration
Pricing
$1,345/0.5 mg | $6,050/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, mutant, minimal vitronectin binding, Protein (Cat# AAA634397)

Full Name
Plasminogen Activator Inhibitor Type 1, mutant, minimal vitronectin binding (PAI-1)
Purity
Highly Purified
>98% pure by SDS PAGE 95 (+/-) 5% active by uPA titration.
Pricing
$1,355/0.5 mg | $6,100/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, stable mutant, Protein (Cat# AAA634434)

Full Name
Plasminogen Activator Inhibitor Type 1, stable mutant, Human (PAI-1)
Purity
Highly Purified
>99% pure by SDS PAGE 98% active by uPA titration.
Pricing
$1,355/0.5 mg | $6,100/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, stable mutant, Murine, Protein (Cat# AAA635129)

Full Name
Plasminogen Activator Inhibitor Type 1, stable mutant, Murine (PAI-1)
Purity
Highly Purified
>98% pure by SDS PAGE 95 ± 5% active by uPA titration.
Pricing
$1,330/0.5 mg | $5,980/5x0.5 mg

Plasminogen Activator Inhibitor Type 1, stable mutant, Rat, Protein (Cat# AAA634703)

Full Name
Plasminogen Activator Inhibitor Type 1, stable mutant, Rat (PAI-1)
Purity
Highly Purified
>98% pure by SDS-PAGE 98 (+/-) 2% active by uPA titration.
Pricing
$1,355/0.5 mg | $6,100/5x0.5 mg

PAI-1, Assay Kit (Cat# AAA480484)

Full Name
Human PAI-1 uPA complex antigen assay
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Pricing
$800/1 Kit | $3,640/5x1 Kit

Plasminogen Activator Inhibitor Type 1 mutant, vitronectin binding, Protein (Cat# AAA634819)

Full Name
Plasminogen Activator Inhibitor Type 1 mutant, vitronectin binding (PAI-1)
Purity
Highly Purified
>98% pure by SDS PAGE 95 (+/-) 5% active by uPA titration.
Pricing
$1,355/0.5 mg | $6,100/5x0.5 mg

PLANH1, Polyclonal Antibody (Cat# AAA839636)

Full Name
PLANH1 antibody
Applications
EIA, IHC, WB
Purity
PLANH1 antibody was purified by Ammonium Sulfate precipitation
Pricing
$415/0.1 mg | $1,850/5x0.1 mg
SDS-Page

PLAU, Recombinant Protein (Cat# AAA206389)

Full Name
PLAU, 21-431aa, Human, His tag, Baculovirus
Gene Names
PLAU; ATF; QPD; UPA; URK; u-PA; BDPLT5
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
$340/0.02 mg | $215/0.005 mg | $1,280/5x0.02 mg

PAI-1 Stable Mutant, Active Protein (Cat# AAA136114)

Full Name
Human PAI-1 Stable Mutant, Low Endotoxin
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
>95% by SDS-PAGE analysis
Pricing
$680/0.1 mg | $2,505/0.5 mg
Structure

RG7834, Inhibitor (Cat# AAA5753818)

Full Name
RG7834
Purity
98.00%
Pricing
$235/2 mg | $270/5 mg | $325/10 mg | $470/25 mg | $640/50 mg | $275/1 mL (in DMSO) | $2,605/5x50 mg

UK-371804, Inhibitor (Cat# AAA579575)

Full Name
UK-371804
Purity
95.8%
Pricing
$210/2 mg | $250/5 mg | $315/10 mg | $455/25 mg | $1,780/5x25 mg
SDS-Page

PAI-1, Active Protein (Cat# AAA8123475)

Full Name
PAI-1 Protein, Rat, Recombinant (hFc Tag)
Gene Names
Serpine1; Pai1; PAI1A; Planh; Pai1aa; RATPAI1A
Purity
>90% as determined by SDS-PAGE
Pricing
$450/0.1 mg | $1,885/5x0.1 mg
SDS-Page

SerpinB2, Active Protein (Cat# AAA8120394)

Full Name
SerpinB2 Protein, Human, Recombinant (GST Tag)
Gene Names
SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201
Purity
>95% as determined by SDS-PAGE
Pricing
$395/0.05 mg | $1,635/5x0.05 mg

UK-371804 HCl, Inhibitor (Cat# AAA5756955)

Full Name
UK-371804 HCl
Purity
98.00%
Pricing
$250/5 mg | $460/25 mg | $1,780/5x25 mg
Structure

UK-371804, Inhibitor (Cat# AAA3603771)

Full Name
UK-371804
Purity
>98% (HPLC)
Pricing
$205/2 mg | $240/5 mg | $305/10 mg | $420/25 mg | $1,615/5x25 mg

Ganoderic acid H, Inhibitor (Cat# AAA5760394)

Full Name
Ganoderic acid H
Purity
98.00%
Pricing
$395/1 mg | $935/5 mg | $3,925/5x5 mg
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