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48 results for "c MET kinase inhibitor" - showing 1-48
Western Blot (WB)
(WB Analysis. HeLa whole cell lysate.)
14-3-3, gamma, Monoclonal Antibody (Cat# AAA632711)
Full Name
14-3-3, gamma (Protein Kinase C Inhibitor Protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein, gamma Polypeptide, YWHAG)
Gene Names
YWHAG; 14-3-3GAMMA
Reactivity
Bovine, Chicken, Human, Mouse, Rat0
Applications
WB
Purity
Ascites
Ascites.
Ascites.
Pricing
$655/0.1 mL | $2,940/5x0.1 mL
Western Blot (WB)
(Western Blot: 14-3-3 gamma detected in lysates using MBS632857 Lane 1: HeLa cell lysate,|Lanes 2 & 3: bengamide treated lysates (8h and 24h, respectively).)
14-3-3, gamma, Monoclonal Antibody (Cat# AAA632857)
Full Name
14-3-3, gamma (Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, YWHAG)
Gene Names
YWHAG; 14-3-3GAMMA
Reactivity
Human
Applications
WB
Purity
Ascites
Ascites
Ascites
Pricing
$610/0.1 mL | $2,730/5x0.1 mL
14-3-3, gamma, Monoclonal Antibody (Cat# AAA631763)
Full Name
14-3-3, gamma (Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, YWHAG)
Gene Names
YWHAG; 14-3-3GAMMA
Reactivity
Human
Applications
WB
Purity
Ascites
Mouse ascites
Mouse ascites
Pricing
$580/0.1 mL | $2,595/5x0.1 mL
Testing Data
(Image: WB Analysis. HeLa whole cell lysate. Lanes 2 and 3: bengamide treated lysates (8h and 24h, respectively).)
14-3-3 gamma [KC21], Antibody (Cat# AAA555021)
Full Name
Mouse Monoclonal Anti-14-3-3 gamma [KC21]
Gene Names
YWHAG; PPP1R170; 14-3-3GAMMA
Reactivity
Human
Applications
WB
Pricing
$425/0.1 mL | $1,760/5x0.1 mL
SDS-PAGE
14-3-3 beta / YWHAB, Recombinant Protein (Cat# AAA2546049)
Full Name
Recombinant Human 14-3-3 beta / YWHAB Protein
Gene Names
YWHAB; HS1; GW128; YWHAA; KCIP-1; HEL-S-1
Purity
> 93 % as determined by SDS-PAGE
Pricing
$440/0.05 mg | $675/0.1 mg | $3,030/5x0.1 mg
14-3-3 beta / YWHAB, Recombinant Protein (Cat# AAA2546050)
Full Name
Recombinant Human 14-3-3 beta / YWHAB Protein (GST tag)
Gene Names
YWHAB; HS1; GW128; YWHAA; KCIP-1; HEL-S-1
Purity
> 96 % as determined by SDS-PAGE
Pricing
$440/0.05 mg | $675/0.1 mg | $3,030/5x0.1 mg
Protein Kinase C, eta Inhibitor, Pseudosubstrate, Inhibitor (Cat# AAA655411)
Full Name
Protein Kinase C, eta Inhibitor, Pseudosubstrate
Purity
Highly Purified
~80% by HPLC analysis (purity based on peak area)
~80% by HPLC analysis (purity based on peak area)
Pricing
$325/1 mg | $1,460/5x1 mg
Testing Data
(specific activity)
c-Met, Active Protein (Cat# AAA637531)
Full Name
c-Met, Recombinant, Human (Hepatocyte Growth Factor, Scatter Factor Receptor, HGF, SF)
Gene Names
MET; c-Met
Purity
Highly Purified
~ 60%
~ 60%
Pricing
$675/0.01 mg | $3,040/5x0.01 mg
Testing Data
(Foretinib (GSK1363089, XL880) is a novel MET and VEGFR2/KDR kinases inhibitor with an IC50 of 0.4 and 0.8 nM for MET and KDR, respectively. Foretinib (GSK1363089, XL880) inhibits HGF receptor family tyrosine kinases with an IC50 of 3 nM for Ron. Foretinib (GSK1363089, XL880) also inhibits KDR, Flt-1, and Flt-4 with IC50 of 0.9, 6.8 and 2.8 nM, respectively. In addition, EXEL-2880 inhibits members of the platelet-derived growth factor receptor family and the angiopoietin-1 receptor Tie-2. Foretinib (GSK1363089, XL880) exhibits modest activity against fibroblast growth factor receptor 1 and epidermal growth factor receptor and is inactive against 50 serine/threonine kinases, including cyclin-dependent kinases and protein kinase C isoforms. To delineate the cellular effect of foretinib (GSK1363089, XL880), VEGF- induced extracellular signal-regulated kinase phosphorylation was used to assess the effect of the compound on phosphorylation of KDR in human umbilical vein endothelial cells that resulted in an IC50 of 16 nM. Foretinib(GSK1363089, XL880) is the 1st orally available small molecule inhibitor of Met to enter the clinic and appears to be generally well tolerated. Anti-tumor activity has been observed and Foretinib may represent an active treatment option for patients with papillary renal-cell carcinoma. [1])
Foretinib, Inhibitor (Cat# AAA8506342)
Full Name
Foretinib (GSK1363089, XL880)
Purity
>99%
Pricing
$440/5 mg | $1,940/5x5 mg
Protein Kinase C, eta Inhibitor, Pseudosubstrate, Myristoylated, Inhibitor (Cat# AAA655428)
Full Name
Protein Kinase C, eta Inhibitor, Pseudosubstrate, Myristoylated
Purity
Highly Purified
~90% by HPLC and MS analysis
~90% by HPLC and MS analysis
Pricing
$325/1 mg | $1,460/5x1 mg
Structure
SGI-1027, Inhibitor (Cat# AAA577339)
Full Name
SGI-1027
Purity
99.45%
Pricing
$205/5 mg | $235/10 mg | $300/25 mg | $425/50 mg | $640/100 mg | $225/1 mL (in DMSO) | $2,605/5x100 mg
Structure
AMG-900, Inhibitor (Cat# AAA578928)
Full Name
AMG-900
Purity
98.0%
Pricing
$210/2 mg | $255/5 mg | $325/10 mg | $510/25 mg | $730/50 mg | $265/1 mL (in DMSO) | $3,025/5x50 mg
Chemical Structure
Capmatinib 2HCl, Inhibitor (Cat# AAA5750411)
Full Name
Capmatinib 2HCl
Purity
99.8%
Pricing
$195/2 mg | $210/5 mg | $225/10 mg | $385/50 mg | $565/100 mg | $775/200 mg | $3,225/5x200 mg
Structure
DCC-2618, Inhibitor (Cat# AAA5750109)
Full Name
DCC-2618
Purity
98.7%
Pricing
$210/2 mg | $245/5 mg | $295/10 mg | $470/25 mg | $785/50 mg | $1,180/100 mg | $245/1 mL (in DMSO) | $5,040/5x100 mg
S49076, Inhibitor (Cat# AAA579641)
Full Name
S49076 HCl
Purity
98.0%
Pricing
$200/1 mg | $230/2 mg | $255/5 mg | $320/10 mg | $425/25 mg | $605/50 mg | $980/100 mg | $4,130/5x100 mg
Chemical Structure
(Chemical structure of PHA 665752 (SIH-421), a MET kinase inhibitor. CAS #: 477575-56-7. Molecular Formula: C32H34Cl2N4O4S. Molecular Weight: 641.61 g/mol.)
PHA 665752, Small Molecule (Cat# AAA808123)
Full Name
PHA 665752
Purity
>98
Pricing
$240/5 mg | $610/25 mg | $2,520/5x25 mg | $870/5x5 mg
CP-724714, Inhibitor (Cat# AAA579919)
Full Name
CP-724714
Purity
98.82%
Pricing
$205/2 mg | $235/5 mg | $295/10 mg | $430/25 mg | $595/50 mg | $835/100 mg | $235/1 mL (in DMSO) | $3,495/5x100 mg
LY2801653, Inhibitor (Cat# AAA579586)
Full Name
LY2801653
Purity
99.56%
Pricing
$215/2 mg | $245/5 mg | $295/10 mg | $480/25 mg | $595/50 mg | $785/100 mg | $275/1 mL (in DMSO) | $3,260/5x100 mg
Structure
c-Met 1, Inhibitor (Cat# AAA5752843)
Full Name
c-Met inhibitor 1
Purity
99.56%
Pricing
$325/5 mg | $380/10 mg | $805/50 mg | $1,270/100 mg | $340/1 mL (in DMSO) | $5,440/5x100 mg
SDS-Page
14-3-3 epsilon, Recombinant Protein (Cat# AAA8120516)
Full Name
14-3-3 epsilon Protein, Human, Recombinant
Gene Names
YWHAE; MDS; MDCR; KCIP-1; 14-3-3E
Purity
>96% as determined by SDS-PAGE
Pricing
$450/0.1 mg | $1,885/5x0.1 mg
Structure
Crizotinib hydrochloride, Inhibitor (Cat# AAA5759203)
Full Name
Crizotinib hydrochloride
Purity
99.67%
Pricing
$170/2 mg | $185/5 mg | $205/10 mg | $225/25 mg | $240/50 mg | $275/100 mg | $360/500 mg | $305/200 mg | $205/1 mL (in DMSO) | $1,350/5x500 mg
Structure
BMS817378, Inhibitor (Cat# AAA5758653)
Full Name
BMS817378
Purity
100.00%
Pricing
$230/1 mg | $305/5 mg | $375/10 mg | $580/25 mg | $800/50 mg | $3,340/5x50 mg
SDS-Page
14-3-3 epsilon, Recombinant Protein (Cat# AAA8120515)
Full Name
14-3-3 epsilon Protein, Human, Recombinant (GST Tag)
Gene Names
YWHAE; MDS; MDCR; KCIP-1; 14-3-3E
Purity
>92% as determined by SDS-PAGE
Pricing
$450/0.1 mg | $1,885/5x0.1 mg
SDS-Page
14-3-3 beta, Recombinant Protein (Cat# AAA8120517)
Full Name
14-3-3 beta Protein, Human, Recombinant (GST Tag)
Gene Names
YWHAB; HS1; GW128; YWHAA; KCIP-1
Purity
>96% as determined by SDS-PAGE
Pricing
$395/0.1 mg | $1,635/5x0.1 mg
SDS-Page
14-3-3 beta, Recombinant Protein (Cat# AAA8120518)
Full Name
14-3-3 beta Protein, Human, Recombinant
Gene Names
YWHAB; HS1; GW128; YWHAA; KCIP-1
Purity
>93% as determined by SDS-PAGE
Pricing
$395/0.1 mg | $1,635/5x0.1 mg
Structure
S49076 hydrochloride, Inhibitor (Cat# AAA3601116)
Full Name
S49076 hydrochloride
Purity
>98% (HPLC)
Pricing
$225/2 mg | $245/5 mg | $305/10 mg | $395/25 mg | $560/50 mg | $895/100 mg | $3,735/5x100 mg
Structure
Savolitinib, Inhibitor (Cat# AAA5764463)
Full Name
Savolitinib
Purity
98.03%
Pricing
$230/5 mg | $265/10 mg | $340/25 mg | $515/50 mg | $795/100 mg | $235/1 mL (in DMSO) | $3,300/5x100 mg
Structure
CSF1R-IN-2, Inhibitor (Cat# AAA5754061)
Full Name
CSF1R-IN-2
Purity
98.00%
Pricing
$230/1 mg | $300/5 mg | $365/10 mg | $560/25 mg | $865/50 mg | $1,410/100 mg | $2,055/200 mg | $310/1 mL (in DMSO) | $8,985/5x200 mg
Structure
Merestinib dihydrochloride, Inhibitor (Cat# AAA5755136)
Full Name
Merestinib dihydrochloride
Purity
98.00%
Pricing
$240/2 mg | $280/5 mg | $355/10 mg | $705/50 mg | $1,065/100 mg | $330/1mL*10mM (in DMSO) | $4,505/5x100 mg
Macrocarpal B, Inhibitor (Cat# AAA5762714)
Full Name
Macrocarpal B
Purity
98.00%
Pricing
$335/1 mg | $1,220/5x1 mg
Structure
Norcantharidin, Inhibitor (Cat# AAA5752012)
Full Name
Norcantharidin
Purity
98.00%
Pricing
$195/10 mg | $215/25 mg | $700/5x25 mg
Cabozantinib hydrochloride, Inhibitor (Cat# AAA5751609)
Full Name
Cabozantinib hydrochloride (849217-68-1 (free base))
Purity
98.00%
Pricing
$195/2 mg | $210/5 mg | $240/10 mg | $300/25 mg | $375/50 mg | $480/100 mg | $705/200 mg | $2,905/5x200 mg
Bozitinib, Inhibitor (Cat# AAA3843018)
Full Name
Bozitinib
Purity
>98%
Pricing
$455/5 mg | $805/10 mg | $2,360/50 mg | $10,570/5x50 mg
Structure
SAR125884 hydrochlorid, Inhibitor (Cat# AAA5752033)
Full Name
SAR125884 hydrochlorid (1116743-46-4 (free base))
Purity
98.00%
Pricing
$205/1 mg | $235/5 mg | $290/10 mg | $445/25 mg | $730/50 mg | $3,025/5x50 mg
Structure
BMS-2, Inhibitor (Cat# AAA5759133)
Full Name
BMS-2
Purity
99.70%
Pricing
$240/1 mg | $330/5 mg | $445/10 mg | $730/25 mg | $3,020/5x25 mg
Chemical Structure
Capmatinib 2HCl.H2O, Inhibitor (Cat# AAA5764984)
Full Name
Capmatinib 2HCl.H2O
Purity
0.9984
Pricing
$195/2 mg | $225/5 mg | $240/10 mg | $305/25 mg | $400/50 mg | $595/100 mg | $970/200 mg | $4,100/5x200 mg
Structure
Glumetinib, Inhibitor (Cat# AAA5751824)
Full Name
Glumetinib
Purity
100.00%
Pricing
$250/5 mg | $305/10 mg | $550/50 mg | $805/100 mg | $3,350/5x100 mg
Structure
S49076, Inhibitor (Cat# AAA3601115)
Full Name
S49076
Purity
>98% (HPLC)
Pricing
$205/2 mg | $235/5 mg | $250/10 mg | $355/25 mg | $500/50 mg | $830/100 mg | $3,440/5x100 mg
Structure
Glesatinib hydrochloride, Inhibitor (Cat# AAA5754900)
Full Name
Glesatinib hydrochloride
Purity
98.00%
Pricing
$400/5 mg | $510/10 mg | $895/25 mg | $1,400/50 mg | $1,910/100 mg | $520/1mL*10mM (in DMSO) | $8,300/5x100 mg
Structure
PF-04217903 methanesulfonate, Inhibitor (Cat# AAA5753668)
Full Name
PF-04217903 methanesulfonate
Purity
98.00%
Pricing
$215/5 mg | $240/10 mg | $405/50 mg | $635/100 mg | $225/1mL*10mM (in DMSO) | $2,575/5x100 mg
Structure
SGI-7079, Inhibitor (Cat# AAA3607208)
Full Name
SGI-7079
Purity
>98% (HPLC)
Pricing
$200/2 mg | $225/5 mg | $255/10 mg | $375/25 mg | $580/50 mg | $800/100 mg | $3,295/5x100 mg
Hepln-13, Inhibitor (Cat# AAA5765632)
Full Name
Hepln-13
Purity
0.9983
Pricing
$240/1 mg | $330/5 mg | $465/10 mg | $850/25 mg | $1,355/50 mg | $1,975/100 mg | $2,885/200 mg | $340/1 mL (in DMSO) | $12,715/5x200 mg
Chemical Structure
JUN04542, Inhibitor (Cat# AAA5765173)
Full Name
JUN04542
Purity
0.9951
Pricing
$270/1 mg | $370/5 mg | $475/10 mg | $755/25 mg | $1,025/50 mg | $1,410/100 mg | $6,080/5x100 mg
Structure
Capmatinib hydrochloride, Inhibitor (Cat# AAA5759217)
Full Name
Capmatinib hydrochloride (free base)
Purity
99.12%
Pricing
$200/2 mg | $215/5 mg | $245/10 mg | $315/25 mg | $400/50 mg | $545/100 mg | $2,180/5x100 mg
Structure
Mibampator, Inhibitor (Cat# AAA5755145)
Full Name
Mibampator
Purity
98.00%
Pricing
$425/5 mg | $560/10 mg | $1,400/50 mg | $1,910/100 mg | $455/1mL*10mM (in DMSO) | $8,300/5x100 mg
Ningetinib Tosylate, Inhibitor (Cat# AAA5764299)
Full Name
Ningetinib Tosylate
Purity
98.00%
Pricing
$210/2 mg | $235/5 mg | $280/10 mg | $395/25 mg | $575/50 mg | $890/100 mg | $1,265/200 mg | $295/1 mL (in DMSO) | $5,420/5x200 mg
MK-8033, Inhibitor (Cat# AAA5764472)
Full Name
MK-8033
Purity
98.00%
Pricing
$2,220/100 mg | $6,770/500 mg | $3,395/200 mg
Ningetinib, Inhibitor (Cat# AAA5764279)
Full Name
Ningetinib
Purity
99.24%
Pricing
$230/5 mg | $265/10 mg | $365/25 mg | $520/50 mg | $795/100 mg | $3,300/5x100 mg
