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68 results for "ROCK Inhibitor" - showing 1-50
Structure
Y-27632 2, Inhibitor (Cat# AAA577605)
Full Name
Y-27632 dihydrochloride
Purity
99.66%
Pricing
$175/2 mg | $195/5 mg | $205/10 mg | $250/25 mg | $305/50 mg | $420/100 mg | $585/200 mg | $2,365/5x200 mg
Chemical Structure
RKI-1447, Inhibitor (Cat# AAA386064)
Full Name
RKI-1447
Purity
>98%
Pricing
$135/5 mg | $170/10 mg | $325/25 mg | $510/50 mg | $190/1 mL (in DMSO) | $2,250/5x50 mg
Western Blot (WB)
(Western blot detection of RhoGDI in C6, Jurkat, K562, 3T3 and Hela cell lysates using RhoGDI mouse mAb (1:2000 diluted).Predicted band size:26KDa.Observed band size:26KDa.)
RhoGDI, Monoclonal Antibody (Cat# AAA476324)
Full Name
Anti-RhoGDI Mouse mAb
Gene Names
ARHGDIA; GDIA1; NPHS8; RHOGDI; RHOGDI-1; HEL-S-47e
Reactivity
Human, Mouse, Rat
Applications
WB
Pricing
$440/0.1 mL | $1,530/5x0.1 mL
Western Blot (WB)
(Western Blot: Untreated C2C12 lysate (Lane 1), and pervanadate treated C2C12 lysate (Lane 2) were resolved by electrophoresis, transferred to nitrocellulose and probed with MBS616540 (0.5ug/ml). Proteins were visualized using an IgG (HRP) goat anti-rabbit and a chemiluminescence detection system. Arrow indicates phosphorylated MYPT1 substrate (80kD).)
MYPT1, Polyclonal Antibody (Cat# AAA616540)
Full Name
MYPT1, phosphorylated (Thr853/Thr850) (Myosin Phosphatase 1)
Gene Names
PPP1R12A; MBS; MYPT1; MGC133042
Reactivity
Chicken, Human, Mouse, Rat
Applications
WB
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Pricing
$570/0.1 mg | $860/0.2 mg | $3,865/5x0.2 mg
Western Blot (WB)
(Western Blot: Untreated C2C12 lysate (Lane 1), and pervanadate treated C2C12 lysate (Lane 2) were resolved by electrophoresis, transferred to nitrocellulose and probed with M9925-08 (0.5ug/ml). Proteins were visualized using an IgG (HRP) goat anti-rabbit and a chemiluminescence detection system. Arrow indicates phosphorylated MYPT1 substrate (80kD).)
MYPT1, Polyclonal Antibody (Cat# AAA622885)
Full Name
MYPT1, phosphorylated (Thr853/Thr850) (Glycerol Free) (Myosin Phosphatase 1)
Gene Names
PPP1R12A; MBS; MYPT1; MGC133042
Reactivity
Chicken, Human, Mouse, Rat
Applications
WB
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Pricing
$970/0.2 mg | $4,360/5x0.2 mg
Y-27632, Inhibitor (Cat# AAA515044)
Full Name
Y-27632
Pricing
$215/5 mg | $485/25 mg | $1,955/5x25 mg
Western Blot (WB)
(Western Blot analysis of extracts from 293 cells, untreated or treated with the ROCK inhibitor Y27632 (2 minutes at 10uM) using MBS6004571 or M9925-01C. was pre-incubated as indicated with phospho-MYPT1 (Thr696) peptide or nonphospho-MYPT1 (Thr696) peptide.)
MYPT1, Polyclonal Antibody (Cat# AAA6004571)
Full Name
MYPT1, phosphorylated (Thr696) (Myosin Phosphatase Target Subunit 1, Myosin Phosphatase-targeting Subunit 1, MBS, MGC133042, Protein Phosphatase 1 Regulatory Subunit 12A, PPP1R12A, Protein Phosphatase Myosin-binding Subunit)
Gene Names
PPP1R12A; MBS; M130; MYPT1
Reactivity
Human, Monkey, Mouse, Rat
Applications
WB
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Pricing
$660/0.1 mL | $2,955/5x0.1 mL
Molecular Structure
Lapatinib, Inhibitor (Cat# AAA515024)
Full Name
Lapatinib
Purity
>98% (TLC); NMR (Conforms)
Pricing
$185/10 mg | $315/50 mg | $1,195/5x50 mg
Structure
(Structure formula of 029603 (Rho Kinase Inhibitor))
Rho Kinase Inhibitor, Biochemical (Cat# AAA6014576)
Full Name
Rho Kinase Inhibitor (H-1152, H-1152P, (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine, 2HCl, ROCK Inhibitor)
Purity
Highly Purified
95% (HPLC)
95% (HPLC)
Pricing
$635/1 mg | $1,070/5 mg | $4,810/5x5 mg
Alpha-1-antiproteinase (Serpina1), Recombinant Protein (Cat# AAA1431240)
Full Name
Recombinant Mus saxicola Alpha-1-antiproteinase (Serpina1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,990/1 mg (E-Coli) | $2,365/1 mg (Yeast) | $3,520/1 mg (Baculovirus) | $1,800/0.1 mg (Baculovirus) | $2,390/0.1 mg (Mammalian-Cell) | $1,110/0.1 mg (E-Coli) | $1,190/0.1 mg (Yeast) | $6,075/0.5 mg (Mammalian-Cell) | $1,250/0.02 mg (Baculovirus) | $1,520/0.02 mg (Mammalian-Cell) | $925/0.02 mg (E-Coli) | $1,045/0.02 mg (Yeast)
Testing Data
(GSK429286A is a cell-permeable, selective Rho-associated kinase (ROCK) inhibitor with an IC50 of 14 nM. Not only was GSK429286A a potent ROCK1 inhibitor, but GSK429286A also possessed exciting selectivity (30-fold) against a panel of 33 kinases, including RSK1 (IC50 = 3.1 uM) and p70S6K (Ic50 = 2.85 uM). ROCKs are serine/threonine specific protein kinases which play a crucial role in organization of the actin cytoskeleton. ROCK inhibitors have been found to prevent apoptosis, as well as to enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency. Because of GSK429286A)
Chemical Structure
(Chemical structure of Y 27632 (SIH-486), a ROCK family kinase inhibitor. CAS #: 146986-50-7. Molecular Formula: C14H23Cl2N3O. Molecular Weight: 320.3 g/mol.)
Y 27632, Small Molecule (Cat# AAA808185)
Full Name
Y 27632
Purity
>=98% (HPLC)
Pricing
$205/1 mg | $360/5 mg | $700/5x1 mg | $1,400/5x5 mg
Chemical Structure
(Chemical structure of Fasudil (SIH-371), a ROCK inhibitor. CAS #: 103745-39-7. Molecular Formula: C14H17 N3O2S•HCl. Molecular Weight: 327.83 g/mol.)
Fasudil, Small Molecule (Cat# AAA808075)
Full Name
Fasudil
Purity
>=98% (TLC); NMR (Conforms)
Pricing
$240/10 mg | $590/50 mg | $860/5x10 mg | $2,410/5x50 mg
GSK180736A, Inhibitor (Cat# AAA579642)
Full Name
GSK180736A
Purity
98.4%
Pricing
$205/2 mg | $215/5 mg | $235/10 mg | $305/25 mg | $440/50 mg | $705/100 mg | $215/1 mL (in DMSO) | $2,905/5x100 mg
GSK269962A, Inhibitor (Cat# AAA579646)
Full Name
GSK269962A
Purity
99.1%
Pricing
$205/2 mg | $230/5 mg | $290/10 mg | $440/25 mg | $720/50 mg | $985/100 mg | $245/1 mL (in DMSO) | $4,155/5x100 mg
Structure
Ripasudil hydrochloride dihydrate, Inhibitor (Cat# AAA5764566)
Full Name
Ripasudil hydrochloride dihydrate
Purity
100.00%
Pricing
$290/5 mg | $370/10 mg | $675/25 mg | $1,055/50 mg | $1,625/100 mg | $7,035/5x100 mg
Structure
ZINC00881524, Inhibitor (Cat# AAA579993)
Full Name
ZINC00881524
Purity
99.5%
Pricing
$170/2 mg | $185/5 mg | $205/10 mg | $240/25 mg | $285/50 mg | $350/100 mg | $205/1 mL (in DMSO) | $1,310/5x100 mg
Structure
Y-33075 dihydrochloride, Inhibitor (Cat# AAA5754152)
Full Name
Y-33075 dihydrochloride
Purity
98.00%
Pricing
$235/2 mg | $245/5 mg | $305/10 mg | $805/50 mg | $1,225/100 mg | $230/1 mL (in DMSO) | $5,250/5x100 mg
Structure
GSK-180736A, Inhibitor (Cat# AAA3606040)
Full Name
GSK-180736A
Purity
>98% (HPLC)
Pricing
$200/2 mg | $210/5 mg | $230/10 mg | $300/25 mg | $405/50 mg | $645/100 mg | $2,625/5x100 mg
Structure
Merestinib dihydrochloride, Inhibitor (Cat# AAA5755136)
Full Name
Merestinib dihydrochloride
Purity
98.00%
Pricing
$240/2 mg | $280/5 mg | $355/10 mg | $705/50 mg | $1,065/100 mg | $330/1mL*10mM (in DMSO) | $4,505/5x100 mg
Structure
BDP5290, Inhibitor (Cat# AAA3610644)
Full Name
BDP5290
Purity
>98% (HPLC)
Pricing
$235/2 mg | $285/5 mg | $370/10 mg | $565/25 mg | $775/50 mg | $3,220/5x50 mg
Structure
Ripasudil free base, Inhibitor (Cat# AAA3610875)
Full Name
Ripasudil free base
Purity
>98% (HPLC)
Pricing
$275/5 mg | $340/10 mg | $570/25 mg | $905/50 mg | $3,790/5x50 mg
Chemical Structure
ROCK, Inhibitor (Cat# AAA3840940)
Full Name
ROCK inhibitor
Purity
>98%
Pricing
$395/5 mg | $570/10 mg | $1,320/50 mg | $5,870/5x50 mg
Structure
Y27632, Inhibitor (Cat# AAA3602009)
Full Name
Y27632
Purity
>98% (HPLC)
Pricing
$250/10 mg | $570/50 mg | $2,260/5x50 mg
Structure
BDP5290, Inhibitor (Cat# AAA5752449)
Full Name
BDP5290
Purity
98.00%
Pricing
$250/2 mg | $305/5 mg | $405/10 mg | $700/25 mg | $1,155/50 mg | $1,905/100 mg | $280/1 mL (in DMSO) | $8,315/5x100 mg
Chemical Structure
Hydroxyfasudil Hydrochloride, Inhibitor (Cat# AAA5750424)
Full Name
Hydroxyfasudil Hydrochloride
Purity
99.8%
Pricing
$190/2 mg | $210/5 mg | $235/10 mg | $290/50 mg | $400/100 mg | $210/1 mL (in DMSO) | $1,525/5x100 mg
Structure
Rho-Kinase-IN-1, Inhibitor (Cat# AAA3844848)
Full Name
Rho-Kinase-IN-1
Purity
>98%
Pricing
$415/5 mg | $675/10 mg | $1,910/50 mg | $3,750/100 mg
Structure
Hydroxyfasudil Hydrochloride, Inhibitor (Cat# AAA3607328)
Full Name
Hydroxyfasudil Hydrochloride
Purity
>98% (HPLC)
Pricing
$190/2 mg | $215/5 mg | $230/10 mg | $475/50 mg | $770/100 mg | $3,180/5x100 mg
Structure
Structure
Ripasudil, Inhibitor (Cat# AAA5758386)
Full Name
Ripasudil free base
Purity
98.57%
Pricing
$220/1 mg | $290/5 mg | $365/10 mg | $620/25 mg | $995/50 mg | $4,195/5x50 mg
Structure
Rho-Kinase-IN-1, Inhibitor (Cat# AAA5753820)
Full Name
Rho-Kinase-IN-1
Purity
98.00%
Pricing
$425/5 mg | $600/10 mg | $970/25 mg | $1,525/50 mg | $2,035/100 mg | $365/1mL*10mM (in DMSO) | $8,870/5x100 mg
Cucurbitacin A, Inhibitor (Cat# AAA5760267)
Full Name
Cucurbitacin A
Purity
98.00%
Pricing
$690/1 mg | $2,830/5x1 mg
Narciclasine, Inhibitor (Cat# AAA5764438)
Full Name
Narciclasine
Purity
98.00%
Pricing
$305/1 mg | $830/5 mg | $3,445/5x5 mg
Chemical Structure
ROCK inhibitor-1, Inhibitor (Cat# AAA3840941)
Full Name
ROCK inhibitor-1
Purity
>98%
Pricing
$410/5 mg | $585/10 mg | $1,320/50 mg | $5,870/5x50 mg
Chemical Structure
H-1152 dihydrochloride, Inhibitor (Cat# AAA3840840)
Full Name
H-1152 dihydrochloride
Purity
>98%
Pricing
$215/5 mg | $340/10 mg | $685/50 mg | $3,025/5x50 mg
Chemical Structure
Ripasudil, Inhibitor (Cat# AAA3841239)
Full Name
Ripasudil
Purity
>98%
Pricing
$230/5 mg | $340/10 mg | $685/25 mg | $3,025/5x25 mg
HA-1077, Inhibitor (Cat# AAA3840048)
Full Name
HA-1077 dihydrochloride
Purity
>98%
Pricing
$140/50 mg | $180/100 mg | $260/250 mg | $1,120/5x250 mg
Y-27632, Inhibitor (Cat# AAA3845878)
Full Name
Y-27632
Purity
>98%
Pricing
$155/5 mg | $210/10 mg | $495/50 mg | $945/100 mg | $4,200/5x100 mg
Structure
Y-27632 dihydrochloride, Inhibitor (Cat# AAA3601202)
Full Name
Y-27632 dihydrochloride
Purity
>98% (HPLC)
Pricing
$190/5 mg | $205/10 mg | $240/25 mg | $300/50 mg | $390/100 mg | $545/200 mg | $2,155/5x200 mg
Structure
TG100713, Inhibitor (Cat# AAA3607659)
Full Name
TG100713
Purity
>98% (HPLC)
Pricing
$190/2 mg | $205/5 mg | $245/10 mg | $315/25 mg | $455/50 mg | $715/100 mg | $2,930/5x100 mg
Structure
ZINC00881524, Inhibitor (Cat# AAA3607536)
Full Name
ZINC00881524
Purity
>98% (HPLC)
Pricing
$210/2 mg | $245/5 mg | $315/10 mg | $480/25 mg | $755/50 mg | $1,240/100 mg | $5,295/5x100 mg
Structure
Netarsudil dihydrochloride, Inhibitor (Cat# AAA3601023)
Full Name
Netarsudil dihydrochloride
Purity
>98% (HPLC)
Structure
(1R,2S)-VU0155041, Inhibitor (Cat# AAA5754177)
Full Name
(1R,2S)-VU0155041
Purity
98.00%
Pricing
$210/5 mg | $240/10 mg | $330/25 mg | $215/1mL*10mM (in DMSO) | $1,180/5x25 mg
SR-3677, Inhibitor (Cat# AAA5764442)
Full Name
SR-3677
Purity
98.00%
Pricing
$200/2 mg | $215/5 mg | $240/10 mg | $310/25 mg | $450/50 mg | $715/100 mg | $1,015/200 mg | $230/1 mL (in DMSO) | $4,305/5x200 mg
Fasudil, Inhibitor (Cat# AAA3846055)
Full Name
Fasudil
Purity
>98%
Pricing
$420/1 mg | $1,155/5 mg | $1,900/10 mg | $8,485/5x10 mg
Chemical Structure
Hydroxyfasudil hydrochloride, Inhibitor (Cat# AAA3840855)
Full Name
Hydroxyfasudil hydrochloride
Purity
>98%
Pricing
$170/10 mg | $310/25 mg | $545/50 mg | $2,385/5x50 mg
ZINC00881524, Inhibitor (Cat# AAA3844922)
Full Name
ZINC00881524
Purity
>98%
Pricing
$135/10 mg | $190/25 mg | $265/50 mg | $420/100 mg | $1,830/5x100 mg
Chemical Structure
BDP5290, Inhibitor (Cat# AAA3841941)
Full Name
BDP5290
Purity
>98%
Pricing
$200/2 mg | $285/5 mg | $420/10 mg | $1,435/50 mg | $6,400/5x50 mg
Chemical Structure
RKI-1313, Inhibitor (Cat# AAA386602)
Full Name
RKI-1313
Purity
>98%
Pricing
$160/5 mg | $220/10 mg | $625/50 mg | $2,760/5x50 mg
