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250 results for " p110alpha" - showing 1-50


Typical Testing Data/Standard Curve (for reference only)

phosphoinositide-3-kinase, catalytic, alpha polypeptide, ELISA Kit (Cat# AAA703575)

Full Name
Mouse Phosphotylinosital 3 kinase, PI3K ELISA Kit
Gene Names
Pik3ca; p110; caPI3K; p110alpha; 6330412C24Rik
Reactivity
Mouse
Pricing
$615/48-Strip-Wells | $890/96-Strip-Wells | $265/24-Strip-Wells (LIMIT 1) | $3,185/5x96-Strip-Wells | $6,110/10x96-Strip-Wells
Western Blot (WB) (Western Blot analysis of Hela cells using PI 3-kinase p110? Polyclonal Antibody at dilution of 1:2000.)

PI 3-kinase p110alpha, Polyclonal Antibody (Cat# AAA2538848)

Full Name
PI 3-kinase p110alpha Polyclonal Antibody
Reactivity
Human, Mouse
Applications
WB, IHC, EIA
Purity
Antigen Affinity Purified
Pricing
$130/0.02 mL | $395/0.2 mL | $250/0.12 mL | $170/0.06 mL | $1,715/5x0.2 mL
Western Blot (WB) (Western blot analysis of PI3 kinase P110alpha expression in rat liver)

PI3 kinase P110alpha, Polyclonal Antibody (Cat# AAA9601285)

Full Name
PI3 kinase P110alpha Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot analysis using PIK3CA mAb against human PIK3CA (AA)

PIK3CA, Monoclonal Antibody (Cat# AAA476272)

Full Name
Anti-PIK3CA Mouse mAb
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human
Applications
WB, ICC, FC/FACS
Pricing
$440/0.1 mL | $1,520/5x0.1 mL
Western Blot (WB) (Western blot analysis of extracts of Mouse kidney using PIK3CA Polyclonal Antibody at dilution of 1:1000.)

PI 3 kinase p110 alpha, Polyclonal Antibody (Cat# AAA2554577)

Full Name
PI 3 kinase p110 alpha Polyclonal Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Affinity purification
Pricing
$405/0.2 mL | $255/0.12 mL | $180/0.06 mL | $1,825/5x0.2 mL
Western Blot (WB) (Western blot analysis of anti-PI3KCA Pab in HeLa cell lysate. PI3KCA (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.)

PI3KCA, Polyclonal Antibody (Cat# AAA9200737)

Full Name
PI3KCA Antibody (C-term)
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human (Predicted Reactivity: Bovine)
Applications
WB, EIA, FC, IHC-p
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$415/0.4 mL | $185/0.08 mL | $1,625/5x0.4 mL
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using PIK3CA antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)

PIK3CA, Polyclonal Antibody (Cat# AAA125271)

Full Name
PIK3CA Polyclonal Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Affinity Purification
Pricing
$180/0.02 mL | $210/0.05 mL | $285/0.1 mL | $430/0.2 mL | $1,790/5x0.2 mL
Western Blot (WB) (Western blot analysis of Jurkat, using PIK3CA antibody. The lane on the left is treated with the antigen-specific peptide.)

PIK3CA, Polyclonal Antibody (Cat# AAA9606729)

Full Name
PIK3CA Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot analysis of anti-PIK3CA Antibody (Center) Pab in K562 cell line lysates (35ug/lane). PIK3CA (arrow) was detected using the purified Pab)

PI3KCA, Polyclonal Antibody (Cat# AAA9211098)

Full Name
PI3KCA Antibody (Center)
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human
Applications
WB, EIA, IHC
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$415/0.4 mL | $185/0.08 mL | $1,625/5x0.4 mL
Western Blot (WB) (Western blot analysis of PIK3CA expression in Jurkat cell lysate, The lane on the left is treated with the antigen-specific peptide.)

PIK3CA, Polyclonal Antibody (Cat# AAA9604139)

Full Name
PIK3CA Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts of mouse kidney, using PIK3CA Antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)

PIK3CA, Polyclonal Antibody (Cat# AAA9132377)

Full Name
PIK3CA Polyclonal Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Affinity Purification
Pricing
$180/0.02 mL | $210/0.05 mL | $285/0.1 mL | $430/0.2 mL | $1,790/5x0.2 mL
Immunohistochemistry (IHC) ((2.5ug/ml) staining of paraffin embedded Human Brain (Cerebellar Cortex). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)

PIK3CA/P110alpha, Polyclonal Antibody (Cat# AAA421100)

Full Name
Goat anti-PIK3CA/P110alpha Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Applications
EIA, IHC
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Pricing
$335/0.1 mg

PIK3CA / P110alpha, Blocking Peptide (Cat# AAA426574)

Full Name
PIK3CA / P110alpha Immunizing Peptide
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse, Rat, Dog, Cow
Pricing
$215/0.1 mg
Testing Data #1 (Paraffin embedded human brain (cerebellar cortex) stained with Goat anti human p110alpha (MBS223510))

PI-3 KINASE p110 SUBUNIT ALPHA, Polyclonal Antibody (Cat# AAA223510)

Full Name
GOAT ANTI HUMAN PI-3 KINASE p110 SUBUNIT ALPHA
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Bovine (Expected from Sequence), Dog (Expected from Sequence), Mouse (Expected from Sequence), Rat (Expected from Sequence)
Applications
EIA
Pricing
$625/0.1 mg | $2,670/5x0.1 mg
Testing Data

PK3CA, Polyclonal Antibody (Cat# AAA853456)

Full Name
PK3CA Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human
Applications
EIA, IHC
Pricing
$350/0.2 mL | $570/0.1 mL (Biotin) | $1,515/5x0.2 mL | $570/0.1 mL (FITC) | $570/0.1 mL (AF350) | $570/0.1 mL (AF405) | $570/0.1 mL (AF488) | $570/0.1 mL (AF555) | $570/0.1 mL (AF568)
Typical Testing Data/Standard Curve (for reference only)

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA288168)

Full Name
Bovine Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit
Reactivity
Bovine
Pricing
$430/48-Strip-Wells | $570/96-Strip-Wells | $2,470/5x96-Strip-Wells | $4,620/10x96-Strip-Wells

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA), Recombinant Protein (Cat# AAA964541)

Full Name
Recombinant Human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) , partial
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,675/1 mg (E-Coli) | $2,160/1 mg (Yeast) | $3,235/1 mg (Baculovirus) | $1,645/0.1 mg (Baculovirus) | $2,230/0.1 mg (Mammalian-Cell) | $935/0.1 mg (E-Coli) | $1,095/0.1 mg (Yeast) | $5,915/0.5 mg (Mammalian-Cell) | $1,145/0.02 mg (Baculovirus) | $1,410/0.02 mg (Mammalian-Cell) | $780/0.02 mg (E-Coli) | $930/0.02 mg (Yeast)

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA280579)

Full Name
Human Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) ELISA Kit
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human
Pricing
$435/48-Strip-Wells | $720/96-Strip-Wells | $3,225/5x96-Strip-Wells | $6,160/10x96-Strip-Wells

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Pik3ca), Recombinant Protein (Cat# AAA953664)

Full Name
Recombinant Mouse Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Pik3ca) , partial
Gene Names
Pik3ca; p110; caPI3K; p110alpha; 6330412C24Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Western Blot (WB) (Western blot analysis of PI3K p110 alpha expression in HeLa (A), mouse liver (B) whole cell lysates.)

PI3K p110 alpha, Polyclonal Antibody (Cat# AAA8240067)

Full Name
Anti-PI3K p110 alpha Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
The antibody was purified by immunogen affinity chromatography.
Pricing
$175/0.03 mL | $245/0.1 mL | $325/0.2 mL | $1,410/5x0.2 mL
Typical Testing Data/Standard Curve (for reference only)

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA760879)

Full Name
Human Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit
Gene Names
pik3ca; pi3k; pi3-k; PI3-kinase; PI3K-alpha
Reactivity
Human
Pricing
$330/48-Strip-Wells | $445/96-Strip-Wells | $1,995/5x96-Strip-Wells | $3,805/10x96-Strip-Wells

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA), Recombinant Protein (Cat# AAA966487)

Full Name
Recombinant Bovine Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) , partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
SDS-Page (SDS-PAGE)

p70 S6 Kinase, active, Active Protein (Cat# AAA635532)

Full Name
p70 S6 Kinase, active, Recombinant, Human (p70 S6K)
Gene Names
Pik3ca; p110; caPI3K; p110alpha; 6330412C24Rik
Purity
Purified
65% by densitometry
Pricing
$805/0.01 mg | $3,615/5x0.01 mg
Western Blot (WB) (Western blot analysis of Jurkat cell lines, using PIK3CA antibody.)

PIK3CA, Polyclonal Antibody (Cat# AAA2529096)

Full Name
PIK3CA Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Antigen affinity purification
Pricing
$405/0.2 mL | $255/0.12 mL | $180/0.06 mL | $1,825/5x0.2 mL
Immunohistochemistry (IHC) (Human Heart (formalin-fixed, paraffin-embedded) stained with PIK3CA antibody at 2.5-5ug/ml followed by biotinylated goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

PIK3CA, Polyclonal Antibody (Cat# AAA6006241)

Full Name
PIK3CA, ID (Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit alpha Isoform, PtdIns-3-kinase Subunit alpha, PI3-kinase Subunit alpha, PI3K-alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase 110kD Catalytic Subunit alpha, PtdIns-3-kinase
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human
Applications
EL/EIA, IHC
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Pricing
$735/0.05 mg | $3,290/5x0.05 mg
Western Blot (WB) (Western blot analysis of Jurkat cell lines, using PIK3CA antibody.)

PIK3CA, Antibody (Cat# AAA8505696)

Full Name
PIK3CA Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB
Purity
Affinity purification
Pricing
$330/0.1 mL | $570/0.1 mL (Biotin) | $1,425/5x0.1 mL | $570/0.1 mL (FITC) | $570/0.1 mL (AF350) | $570/0.1 mL (AF405) | $570/0.1 mL (AF488) | $570/0.1 mL (AF555) | $570/0.1 mL (AF568)

PIK3CA, cDNA Clone (Cat# AAA1267033)

Full Name
PIK3CA cDNA Clone
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Pricing
$4,995/5x0.01 mg Plasmid + 5x0.2 mL Glycerol-Stock | $1,110/0.01 mg Plasmid + 0.2 mL Glycerol-Stock
Typical Testing Data/Standard Curve (for reference only)

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA2882390)

Full Name
Mouse Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit
Gene Names
Pik3ca; p110; caPI3K; p110alpha; 6330412C24Rik
Reactivity
Mouse
Pricing
$430/48-Strip-Wells | $570/96-Strip-Wells | $2,470/5x96-Strip-Wells | $4,620/10x96-Strip-Wells

PI3K p110 alpha, Blocking Peptide (Cat# AAA8232316)

Full Name
PI3K p110 alpha Blocking Peptide
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
BL
Purity
>85%
Pricing
$180/1 mg | $335/5 mg | $1,455/5x5 mg
Western Blot (WB) (Western blot analysis of Jurkat cell lines, using PIK3CA antibody.)

PIK3CA, Polyclonal Antibody (Cat# AAA9401380)

Full Name
PIK3CA antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse, Rat
Applications
WB
Purity
Antibodies were purified by affinity purification using immunogen.
Pricing
$300/0.05 mL | $390/0.1 mL | $1,610/5x0.1 mL
Typical Testing Data

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA762690)

Full Name
Mouse Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit
Gene Names
pik3ca; pi3k; pi3-k; PI3-kinase; PI3K-alpha
Reactivity
Mouse
Pricing
$330/48-Strip-Wells | $445/96-Strip-Wells | $1,995/5x96-Strip-Wells | $3,805/10x96-Strip-Wells
Testing Data (PP242 is a novel potent and selective mTOR inhibitor with an IC50 of 8 nM. PP242 also shows residual (micromolar) activity against panel of tyrosine kinases. But PP242 was much less active against other PI3K family members with IC50 of 2, 2.2, 0.1, 1.3 and 0.41 uM for p110alpha, p110beta, p110delta, p110gamma and DNA-PK, respectively. PP242 inhibits other PI 3-Kinases only at much higher concentrations. PP242, but not rapamycin, causes death of mouse and human leukemia cells. In vivo, PP242 delays leukemia onset and augments the effects of the current front-line tyrosine kinase inhibitors more effectively than does rapamycin. PP242 was also more effective than rapamycin in achieving cytoreduction and apoptosis in multiple myeloma cells. In addition, PP242 was an effective agent against primary multiple myeloma cells in vitro and growth of 8226 cells in mice. Knockdown of the TORC2 complex protein, rictor, was deleterious to multiple myeloma cells further supporting TORC2 as the critical target for PP242. [1][2][3])

PP242, Inhibitor (Cat# AAA8506459)

Full Name
PP242
Purity
>99%
Pricing
$295/5 mg | $1,255/5x5 mg
Testing Data (PI-103 is a potent, cell-permeable, ATP-competitive PI3K family members inhibitor with IC50 of 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110alpha, mTORC1, PI3-KC2beta, p110delta, mTORC2, p110beta, and p110gamma, respectively. It shows little activity against a wide array of protein kinases at 10 mM. It blocks glioma proliferation by blocking the PI 3-K/Akt pathway in vitro and in vivo. PI-103 was essentially cytostatic for cell lines and induced cell cycle arrest in the G1 phase. In blast cells, PI-103 inhibited leukemic proliferation, the clonogenicity of leukemic progenitors and induced mitochondrial apoptosis, especially in the compartment containing leukemic stem cells. PI-103 had additive proapoptotic effects with etoposide in blast cells and in immature leukemic cells. [1][2][3])

PI-103, Inhibitor (Cat# AAA8506504)

Full Name
PI-103
Purity
>99%
Pricing
$295/5 mg | $1,255/5x5 mg
Testing Data

PI3K, Recombinant Protein (Cat# AAA515587)

Full Name
PI3K (p110 alpha (E542K)/p85 alpha, Active
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Applications
Kinase Assay
Pricing
$435/0.01 mg | $335/0.005 mg | $1,735/5x0.01 mg
Western Blot (WB) (Western Blot analysis of HELA cells using PI 3-kinase p110a Polyclonal Antibody)

PI 3-kinase p110alpha, Polyclonal Antibody (Cat# AAA9411379)

Full Name
PI 3-kinase p110alpha Polyclonal Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse
Applications
WB, IHC, EIA
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pricing
$245/0.05 mL | $305/0.1 mL | $1,230/5x0.1 mL
Testing Data

PI3K, Recombinant Protein (Cat# AAA515584)

Full Name
PI3K (p110 alpha/p85 alpha), Active
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Applications
Kinase Assay
Pricing
$435/0.01 mg | $335/0.005 mg | $1,735/5x0.01 mg
Typical Testing Data/Standard Curve (for reference only)

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA2883462)

Full Name
Human Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human
Pricing
$430/48-Strip-Wells | $570/96-Strip-Wells | $2,470/5x96-Strip-Wells | $4,620/10x96-Strip-Wells

PIK3CG, Polyclonal Antibody (Cat# AAA1488604)

Full Name
Rabbit Anti Human PIK3CG PolyClonal Antibody
Reactivity
Human, Mouse, Rat
Applications
WB
Purity
Affinity Purification
Pricing
$325/0.1 mL | $1,465/5x0.1 mL
Western Blot (WB) (Western blot analysis of PI3 kinase?P110alpha expression in mouse liver)

PI3 kinase P110alpha, Antibody (Cat# AAA8511743)

Full Name
PI3 kinase P110alpha Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human, Mouse
Applications
WB, IHC
Purity
Immunogen affinity purified
Pricing
$235/0.05 mg | $310/0.1 mg | $1,330/5x0.1 mg | $1,015/5x0.05 mg | $465/0.1 mL (Biotin) | $465/0.1 mL (FITC) | $465/0.1 mL (AF350) | $465/0.1 mL (AF405) | $465/0.1 mL (AF488) | $465/0.1 mL (AF555) | $465/0.1 mL (AF568)
Testing Data (PIK-93 is a PI4KIIIbeta inhibitor (IC50 at 19 nM). PIK-93 is the first reported PI4-kinase inhibitor, which is able to inhibit PI4KIIIbeta at low-nanomolar range. In addition, this compound also inhibits potently PI3Kgamma in vitro (IC50 at 16 nM). This compound inhibits p110alpha, p110beta, p110deltawith IC50 of 0.039, 0.59, 0.12 uM. PIK-93 also displays the typical hydrogen bonding to the backbone amide of Val882, and additional ones to the backbone carbonyl of Val882 and between its sulphonamide and Asp964. [1])

PIK-93, Inhibitor (Cat# AAA8506587)

Full Name
PIK-93
Pricing
$295/5 mg | $1,255/5x5 mg

PK3CA (Y317), Blocking Peptide (Cat# AAA9227325)

Full Name
PK3CA Antibody (Y317) Blocking Peptide
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha

PIK3CA, siRNA (Cat# AAA8218470)

Full Name
PIK3CA siRNA (Human)
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
Structure

YM201636, Inhibitor (Cat# AAA578681)

Full Name
YM201636
Purity
95.0%
Pricing
$200/2 mg | $240/5 mg | $315/10 mg | $540/25 mg | $775/50 mg | $1,150/100 mg | $240/1 mL (in DMSO) | $4,900/5x100 mg

PIK3CA, siRNA (Cat# AAA8237222)

Full Name
PIK3CA siRNA (Mouse)
Gene Names
Pik3ca; p110; caPI3K; p110alpha; 6330412C24Rik
Reactivity
Mouse
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
Testing Data (PP121 is a multitargeted dual receptor tyrosine kinases inhibitor with IC50 of 0.052, 1.4, 0.15, 1.1, 0.06, 0.01and 0.002 uM for p110alpha, p110beta, p110delta, p110gamma, DNA-PK, mTOR and PDGFR, respectively. PP121 also inhibits Abl, Hck, Src,Src(T338I), VEGFR2, EGFR EphB4 with IC50 of 0.018, 0.008, 0.014, 0.22, 0.012, 0.26, 0.19 uM, respectively. PP121 exhibits no significant effect on receptor serine/threonine kinases (RSTKs). PP121 blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor. PP121 achieves its dual potency by targeting a residue (Glu310 in Src) that has been structurally conserved between kinase families. PP121 potently and dose-dependently blocked the phosphorylation of Akt, p70S6K and S6 in these cells. [1])

PP-121, Inhibitor (Cat# AAA8506273)

Full Name
PP-121
Pricing
$370/10 mg | $1,620/5x10 mg

Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA9427221)

Full Name
Mouse Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit
Gene Names
Pik3ca; p110; caPI3K; p110alpha; 6330412C24Rik
Reactivity
Mouse
Pricing
$735/96 Tests | $3,385/5x96 Tests
Structure

BGT226, Inhibitor (Cat# AAA578645)

Full Name
BGT226 (NVP-BGT226)
Purity
97.8%
Pricing
$205/1 mg | $215/2 mg | $245/5 mg | $315/10 mg | $520/25 mg | $830/50 mg | $1,105/100 mg | $290/1 mL (in DMSO) | $4,710/5x100 mg
Structure

PF-04691502, Inhibitor (Cat# AAA578814)

Full Name
PF-04691502
Purity
96.3%
Pricing
$190/2 mg | $210/5 mg | $230/10 mg | $265/25 mg | $330/50 mg | $480/100 mg | $205/1 mL (in DMSO) | $1,900/5x100 mg

Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha isoform, ELISA Kit (Cat# AAA9427222)

Full Name
Human Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Reactivity
Human
Pricing
$735/96 Tests | $3,385/5x96 Tests

PI3KCA, Blocking Peptide (Cat# AAA9227460)

Full Name
PI3KCA Antibody (Center) Blocking Peptide
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
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