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25 results for " Pyroptosis" - showing 1-25
Testing Data
(THP-I suspension cells were treated with PMA (5 ng/mL) to induce differentiation into macrophages. After 48 hours, PMA was removed and replaced with fresh medium that was spiked with LPS (10 ng/mL) to induce caspase-1 activation. After 2 hours, cells were stained with FAM-YVAD-FMK for 1 hour, washed, and examined under a fluorescence microscope. The top images reveal many experimental cells, several of which fluoresce green, therefore they have active caspase-1. The lower right image reveals many control cells in the field of view, however the corresponding fluorescence image is dark (lower left); few of these cells have active caspase-1. Data courtesy of Dr. Brian Lee, ICT.)
Pyroptosis/Caspase-1, Assay Kit (Cat# AAA258046)
Full Name
Pyroptosis/Caspase-1 Assay Kit
Pricing
$405/25-50 Tests
Testing Data
()
FLICA 660 Caspase-1, Assay Kit (Cat# AAA258044)
Full Name
FLICA 660 Caspase-1 Assay Kit
Pricing
$335/25-50 Tests
Western Blot (WB)
(Western blot analysis of Interleukin 1beta expression in S3 lysate)
Interleukin 1beta, Polyclonal Antibody (Cat# AAA9601276)
Full Name
Interleukin 1beta Antibody
Gene Names
IL1B; IL-1; IL1F2; IL1-BETA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis of human adrenal lysate using IL1B antibody. The lane on the left is treated with the antigen-specific peptide.)
IL1B, Polyclonal Antibody (Cat# AAA9606910)
Full Name
IL1B Antibody
Gene Names
IL1B; IL-1; IL1F2; IL1-BETA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(IL1B Antibody (Center)(Ascites). 293 cell lysates transiently transfected with the IL1B gene.)
IL1B, Monoclonal Antibody (Cat# AAA9200171)
Full Name
IL1B Antibody (Center) (Ascites)
Gene Names
IL1B; IL-1; IL1F2; IL1-BETA
Reactivity
Human (Predicted Reactivity: Monkey, Rabbit)
Applications
WB, EIA
Pricing
$425/0.1 mL | $1,665/5x0.1 mL
Testing Data
Green Pyroptosis/Caspase-1, Assay Kit (Cat# AAA258377)
Full Name
Green Pyroptosis/Caspase-1 Assay
Gene Names
Gsdmd; DF5L; M2-4; Dfna5l; Gsdmdc1; AW558049; 1810036L03Rik
Applications
Flow Cytometer, Fluorescence Microscope, Fluorescence Plate Reader
Pricing
$700/100-200 Tests
Testing Data
(FAM-FLICA Caspase-1 (WEHD) kit was used to detect pyroptosis in THP-1 monocytes. Cells were labeled with FAM-WEHD-FMK, treated with a negative control (DMSO) or LPS (1 µg/mL, 3 hours) followed by Nigericin (20 µM, 30 minutes) to induce pyroptosis. Following treatment, cells were washed and resuspended in PBS + 0.5% BSA. Cells were then stained with Hoechst 33342, fixed, and viewed using a Logos iRiS Digital Cell Imaging System equipped with a EGFP (Ex 470/30, Em 530/50) and a DAPI (Ex 375/28, Em 460/50) LED filter cubes at 20X. Increased levels of green FAM-FLICA staining (leftmost images) were seen in the LPS + Nigericin-treated cells (upper row of images) compared to DMSO mock-treated cells (lower row of images). Hoechst 33342 staining (middle images) and overlays of both the EGFP and DAPI channels (rightmost images) are also shown.)
FAM-FLICA Caspase 1 WEHD, Assay Kit (Cat# AAA258414)
Full Name
FAM-FLICA Caspase 1 WEHD Assay Kit
Pricing
$695/100 Tests | $315/25 Tests | $3,140/5x100 Tests
Pyroptosis/Caspase-1 Assay, Assay Kit (Cat# AAA258379)
Full Name
Pyroptosis/Caspase-1 Assay, Far Red
Applications
Flow Cytometer, Fluorescence Microscope
Pricing
$435/25 Tests | $1,935/5x25 Tests
Testing Data
(Detection of pyroptosis in JurkatsJurkats were stained with Pyroptosis 660 Caspase-1 Kit for two hours followed by treatment with 10 ?M Nigericin as shown. Pyroptosis could be detected by an increase in active Caspase-1 detected by an increase in 660 far red fluorescence. Data analyzed on the ZE5 Cell Analyzer)
Caspase-1, Detection Kit (Cat# AAA225841)
Full Name
Pyroptosis 660 Caspase-1 Kit
Gene Names
Casp1; Ice; Il1bc
Applications
FC/FACS, IF
Pricing
$675/25 Tests | $3,100/5x25 Tests
NLRC4 / NLR Family CARD Domain-Containing Protein 4, Recombinant Protein (Cat# AAA2902847)
Full Name
Human NLRC4 / NLR Family CARD Domain-Containing Protein 4 Recombinant Protein
Gene Names
NLRC4; CLAN; IPAF; AIFEC; CLAN1; CLANA; CLANB; CLANC; CLAND; FCAS4; CARD12; CLR2.1
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
NLRP3, Polyclonal Antibody (Cat# AAA9612622)
Full Name
Phospho-NLRP3 (Ser198) Antibody
Gene Names
NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
Reactivity
Human
Applications
EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB)
(Western blot analysis of NLRP3 in lysates of RAW 264.7, using NLRP3 Antibody(AF4620).)
NLRP3, Polyclonal Antibody (Cat# AAA9613328)
Full Name
NLRP3 Antibody
Gene Names
NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
Reactivity
Human, Mouse
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (88%), Dog (100%)
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (88%), Dog (100%)
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL
Caspase-1, Detection Kit (Cat# AAA225842)
Full Name
Pyroptosis FAM Caspase-1 Kit
Gene Names
Casp1; Ice; Il1bc
Applications
FC/FACS, IF
Pricing
$625/25 Tests | $2,875/5x25 Tests
Western Blot (WB)
(Western blot analysis of extracts from RAW 264.7, using Phospho-NLRP3(Ser295) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)
NLRP3, Polyclonal Antibody (Cat# AAA9613121)
Full Name
Phospho-NLRP3 (Ser295) Antibody
Gene Names
NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
Reactivity
Human, Mouse
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (88%), Dog (100%)
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (88%), Dog (100%)
Applications
WB, IHC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
NAIP / Baculoviral IAP Repeat-Containing Protein 1, Recombinant Protein (Cat# AAA2902812)
Full Name
Human NAIP / Baculoviral IAP Repeat-Containing Protein 1 Recombinant Protein
Gene Names
NAIP; BIRC1; NLRB1; psiNAIP
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Western Blot (WB)
(Western blot analysis of extracts from Mouse heart, using GSDMD Antibody. The lane on the left was treated with blocking peptide.)
GSDMD, Polyclonal Antibody (Cat# AAA9613059)
Full Name
GSDMD Antibody
Gene Names
GSDMD; DF5L; DFNA5L; FKSG10; GSDMDC1
Reactivity
Human, Mouse
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
GSDMC / Gasdermin-C, Recombinant Protein (Cat# AAA2902931)
Full Name
Human GSDMC / Gasdermin-C Recombinant Protein
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Caspase-1, Detection Kit (Cat# AAA225843)
Full Name
Pyroptosis FAM Caspase-1 Kit
Gene Names
Casp1; Ice; Il1bc
Applications
FC/FACS, IF
Pricing
$1,125/100 Tests | $5,210/5x100 Tests
NLRP3, Polyclonal Antibody (Cat# AAA9613576)
Full Name
NLRP3 Antibody
Gene Names
NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
Reactivity
Human
Applications
EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
NACHT, LRR and PYD domains-containing protein 3 (NLRP3), Recombinant Protein (Cat# AAA9018607)
Full Name
Recombinant Human NACHT, LRR and PYD domains-containing protein 3 (NLRP3), partial
Gene Names
NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,915/1 mg (E-Coli) | $510/0.1 mg (E-Coli) | $310/0.02 mg (E-Coli) | $8,395/5x1 mg (E-Coli)
Western Blot (WB)
IL1 beta, Monoclonal Antibody (Cat# AAA9629040)
Full Name
IL1 beta Mouse Monoclonal Antibody
Gene Names
IL1B; IL-1; IL1F2; IL1-BETA
Reactivity
Human, Mouse, Rat
Applications
WB, EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$280/0.1 mL | $325/0.2 mL | $1,305/5x0.2 mL
NLRP3, Polyclonal Antibody (Cat# AAA9630837)
Full Name
NLRP3 Antibody
Gene Names
NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
Reactivity
Human, Mouse, Rat
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
GSDMA, Polyclonal Antibody (Cat# AAA9629750)
Full Name
GSDMA Antibody
Gene Names
GSDMA; GSDM; FKSG9; GSDM1
Reactivity
Human, Mouse
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
GSDMB, Polyclonal Antibody (Cat# AAA9629046)
Full Name
GSDMB Antibody
Gene Names
GSDMB; GSDML; PP4052; PRO2521
Reactivity
Human
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
