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741 results for " Akt inhibitor" - showing 1-50
Structure
LY294002, Inhibitor (Cat# AAA575724)
Full Name
LY294002
Purity
99.93%
Pricing
$175/5 mg | $185/10 mg | $205/50 mg | $215/100 mg | $245/200 mg | $200/1 mL (in DMSO) | $840/5x200 mg
Structure
3-Methyladenine (3-MA), Inhibitor (Cat# AAA575485)
Full Name
3-Methyladenine (3-MA)
Purity
99.51%
Pricing
$185/25 mg | $205/50 mg | $230/100 mg | $380/500 mg | $275/200 mg | $195/1 mL (in DMSO) | $1,435/5x500 mg
Structure
Rapamycin, Inhibitor (Cat# AAA575148)
Full Name
Rapamycin (Sirolimus)
Purity
99.23%
Pricing
$185/25 mg | $205/50 mg | $215/100 mg | $330/500 mg | $250/200 mg | $200/1 mL (in DMSO) | $1,225/5x500 mg
Immunofluorescence (IF)
(MBS9606751 staining A2780 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.)
p27, Polyclonal Antibody (Cat# AAA9606751)
Full Name
p27 Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Pancreas stained with AKT1 Mouse Monoclonal Antibody (AKT1/2491).)
AKT1, Monoclonal Antibody (Cat# AAA439937)
Full Name
AKT1 (Proto-Oncogene)
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human. Others not known
Applications
IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Testing Data
(Staining of human peripheral blood lymphocytes with Mouse anti Human CD299: Azide Free (MBS210211))
CD229, Monoclonal Antibody (Cat# AAA212512)
Full Name
MOUSE ANTI HUMAN CD229
Gene Names
LY9; hly9; mLY9; CD229; SLAMF3
Applications
FC/FACS, IP
Pricing
$525/0.2 mg | $2,210/5x0.2 mg
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Pancreas stained with AKT1 Mouse Monoclonal Antibody (AKT1/2552).)
AKT1, Monoclonal Antibody (Cat# AAA439938)
Full Name
AKT1 (Proto-Oncogene)
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human. Others not known
Applications
IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Western Blot (WB)
(Western blot analysis of Phospho-p27 Kip1 (Ser10) expression in various lysates)
p27 Kip1, Polyclonal Antibody (Cat# AAA9601095)
Full Name
Phospho-p27 Kip1 (Ser10) Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ICC, EIA
Purity
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis of Phospho-p27 Kip1 (Thr187) expression in various lysates)
p27 Kip1, Polyclonal Antibody (Cat# AAA9601093)
Full Name
Phospho-p27 Kip1 (Thr187) Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ICC, EIA
Purity
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis of p27 Kip1 expression in EGF treated HeLa whole cell lysates, The lane on the left is treated with the antigen-specific peptide.)
p27 Kip1, Polyclonal Antibody (Cat# AAA9601895)
Full Name
p27 Kip1 Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunofluorescence (IF)
(MBS9601094 staining A2780 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.)
p27 Kip1, Polyclonal Antibody (Cat# AAA9601094)
Full Name
Phospho-p27 Kip1 (Thr198) Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human
Applications
WB, IF, ICC, EIA
Purity
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human colon carcinoma stained with AKT1 Recombinant Mouse Monoclonal Antibody (rAKT1/2491).)
AKT1, Antibody (Cat# AAA4380873)
Full Name
AKT1 (Prognostic Marker for Neuroendocrine Tumors)
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human
Applications
IHC
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Western Blot (WB)
(Western blot detection of RhoGDI in C6, Jurkat, K562, 3T3 and Hela cell lysates using RhoGDI mouse mAb (1:2000 diluted).Predicted band size:26KDa.Observed band size:26KDa.)
RhoGDI, Monoclonal Antibody (Cat# AAA476324)
Full Name
Anti-RhoGDI Mouse mAb
Gene Names
ARHGDIA; GDIA1; NPHS8; RHOGDI; RHOGDI-1; HEL-S-47e
Reactivity
Human, Mouse, Rat
Applications
WB
Pricing
$440/0.1 mL | $1,530/5x0.1 mL
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Pancreas stained with AKT1 Mouse Monoclonal Antibody (AKT1/2784).)
AKT1, Monoclonal Antibody (Cat# AAA4380872)
Full Name
AKT1 (Prognostic Marker for Neuroendocrine Tumors)
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human, Mouse
Applications
WB, IHC
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Chemical Structure
AKT inhibitor VIII (AKTI-1/2), Inhibitor (Cat# AAA385220)
Full Name
AKT inhibitor VIII (AKTI-1/2)
Purity
>98%
Pricing
$170/5 mg | $220/10 mg | $395/25 mg | $615/50 mg | $2,705/5x50 mg
SDS-Page
(SDS-PAGE Analysis Purified AKT1 Recombinant Rabbit Monoclonal Antibody (AKT1/3898R). Confirmation of Integrity and Purity of Antibody.)
AKT1, Monoclonal Antibody (Cat# AAA4381592)
Full Name
AKT1 (Prognostic Marker for Neuroendocrine Tumors)
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human
Applications
EIA
Purity
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Immunoflurescence (IF)/Immunocytochemistry (ICC)
(Staining Hela cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. Samples were then incubated with primary Ab(BF8013) and rabbit anti-beta tubulin Ab(AF7011) for 1 hour at 37 degree C. An AlexaFluor594 conjugated goat anti-mouse IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-rabbit IgG(H+L) Ab(Green) were used as the secondary antibody.The nuclear counter stain is DAPI (blue).)
p53, Monoclonal Antibody (Cat# AAA9629032)
Full Name
p53 Mouse monoclonal Antibody
Gene Names
TP53; P53; BCC7; LFS1; TRP53
Reactivity
Human, Mouse
Applications
WB, IF, ICC
Purity
Affinity-chromatography.
Pricing
$280/0.1 mL | $325/0.2 mL | $1,305/5x0.2 mL
Structure
Ipatasertib, Inhibitor (Cat# AAA578815)
Full Name
Ipatasertib (GDC-0068)
Purity
98.3%
Pricing
$180/1 mg | $195/2 mg | $210/5 mg | $230/10 mg | $280/25 mg | $360/50 mg | $480/100 mg | $1,295/500 mg | $2,160/1 g | $715/200 mg | $210/1 mL (in DMSO) | $9,440/5x1 g
Structure
A-674563, Inhibitor (Cat# AAA578707)
Full Name
A-674563
Purity
98.0%
Pricing
$225/1 mg | $250/2 mg | $330/5 mg | $425/10 mg | $650/25 mg | $1,025/50 mg | $1,475/100 mg | $330/1mL*10mM (in DMSO) | $6,340/5x100 mg
Structure
GSK690693, Inhibitor (Cat# AAA578844)
Full Name
GSK690693
Purity
98.0%
Pricing
$200/2 mg | $215/5 mg | $240/10 mg | $310/25 mg | $405/50 mg | $600/100 mg | $225/1 mL (in DMSO) | $2,425/5x100 mg
Testing Data
(Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2)
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, Biochemical (Cat# AAA6074625)
Full Name
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2)
Purity
95% by HPLC
Pricing
$570/1 mg | $685/5 mg | $3,085/5x5 mg
Western Blot (WB)
(Western Blotting Lysates prepared from 3T3-L1 cells (1-4) or COS cells overexpressing WT AS160 (5, 6) or mutant AS160 T642A, treated with PI-3-Kinase inhibitor(5), insulin (1-4, 6-7), were resolved by SDS-PAGE on a 10% polyacrylamide gel and transferred to PVDF. Membrane was blocked with a 5% BSA-TBST buffer for one hour at room temperature, and incubated with MBS614987 for two hours at room temperature in 3% BSA-TBST buffer, following prior incubation with: no peptide (1, 5-7), the non-phosphopeptide corresponding to the immunogen (2), a generic phosphothreonine-containing peptide (3) the phosphopeptide immunogen (4). After washing, membranes were incubated with goat F(ab’)2 anti-rabbit IgG HRP conjugate and bands were detected using the Pierce SuperSignal™ method. The data show that only the phosphopeptide corresponding to AS160 blocks the signal. The data also show that the signal was blocked in cells overexpressing site-directed mutant T642A, indicating the antibody is phosphorylation site specific.)
Akt Substrate, 160kD, Polyclonal Antibody (Cat# AAA614987)
Full Name
Akt Substrate, 160kD, phosphorylated (Thr642) (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)
Gene Names
Akt1; akt; Akt; AKT; Akt/PKB; AKT/PKB; akt1; AKT1; Akt1|PKB; CG4006; D-Akt; dakt; dAkt; dAKT; Dakt; DAkt; dAKT/dPKB; dAkt/PKB; dakt1; dAkt1; dAKT1; Dakt1; DAkt1; DAKT1; DAKT1/PKB; DmelCG4006; dPKB; Dpkb; DPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq;
Reactivity
Human
Applications
EL/EIA, WB
Purity
Affinity Purified
Purified from rabbit serum by affinity chromatography.
Purified from rabbit serum by affinity chromatography.
Pricing
$715/10 Blots | $3,205/5x10 Blots
27Kip1, Blocking Peptide (Cat# AAA9226003)
Full Name
27Kip1 Antibody (C-term) Blocking Peptide
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Western Blot (WB)
(The anti-Phospho-p27Kip1-T187Pab is used in Western blot to detect Phospho-p27Kip1-T187 in HL60 tissue lysate)
Phospho-p27Kip1 (T187), Polyclonal Antibody (Cat# AAA9200928)
Full Name
Phospho-p27Kip1 (T187) Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human (Predicted Reactivity: Hamster)
Applications
WB, EIA, IHC-P
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$425/0.4 mL | $190/0.08 mL | $1,665/5x0.4 mL
Structure
Duvelisib, Inhibitor (Cat# AAA575674)
Full Name
Duvelisib (IPI-145, INK1197)
Purity
99.4%
Pricing
$190/2 mg | $210/5 mg | $230/10 mg | $255/25 mg | $290/50 mg | $370/100 mg | $210/1 mL (in DMSO) | $1,400/5x100 mg
Structure
PF-4708671, Inhibitor (Cat# AAA575813)
Full Name
PF-4708671
Purity
99.7%
Pricing
$205/5 mg | $215/10 mg | $250/25 mg | $290/50 mg | $395/100 mg | $225/1 mL (in DMSO) | $1,500/5x100 mg
Structure
AICAR, Inhibitor (Cat# AAA575260)
Full Name
AICAR (Acadesine)
Purity
99.2%
Pricing
$185/25 mg | $195/50 mg | $215/100 mg | $255/200 mg | $195/1 mL (in DMSO) | $870/5x200 mg
Western Blot (WB)
(Western blot analysis of lysate from MCF-7 cell line, using CDKN1B-Y88. MBS9211878 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.)
CDKN1B-Y88, Polyclonal Antibody (Cat# AAA9211878)
Full Name
CDKN1B-Y88 Antibody
Gene Names
CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity
Human
Predicted Reactivity: Hamster
Predicted Reactivity: Hamster
Applications
WB, EIA
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Pricing
$425/0.4 mL | $190/0.08 mL | $1,665/5x0.4 mL
Testing Data
(GSK690693 is an aminofurazan-derived, novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor. It is selective for the Akt isoforms(inhibits Akt kinases 1, 2, and 3 with IC50 values of 2, 13, and 9 nM respectively)versus the majority of kinases in other families; however, it does inhibit additional members of the AGC kinase family. [1,2]GSK690693 inhibited proliferation and induced apoptosis in a subset of tumor cells with potency consistent with intracellular inhibition of Akt kinase activity. [1]Daily administration of GSK690693 produced significant antitumor activity in mice bearing established human SKOV-3 ovarian, LNCaP prostate, and BT474 and HCC-1954 breast carcinoma xenografts. [1])
GSK690693, Inhibitor (Cat# AAA8506383)
Full Name
GSK690693
Purity
>99%
Pricing
$1,535/10 mg | $6,870/5x10 mg
Western Blot (WB)
(Western Blot analysis of extracts from PDGF, wortmannin and LY294002 treated NIH/3T3 cells, using A1124-02 (A); A1124-92 (B) or A1124-03 (C). D is an analysis of Akt activity in PDGF,wortmannin and LY294002 treated NIH/3T3 cells, using Akt Kinase (Rac PKa, PKBa) Assay Kit BioAssay™ (A1125-45).)
LY294002, Inhibitor (Cat# AAA655326)
Full Name
LY294002 (PI 3 Kinase Inhibitor, 2-(4-Morpholinyl)-8-phenyl-4H-1- benzopyran-4-one)
Pricing
$360/0.5 mg | $1,620/5x0.5 mg
Structure
BKM120, Inhibitor (Cat# AAA577126)
Full Name
BKM120 (NVP-BKM120, Buparlisib)
Purity
97.22%
Pricing
$200/5 mg | $215/10 mg | $240/50 mg | $265/100 mg | $350/200 mg | $200/1 mL (in DMSO) | $1,305/5x200 mg
Akt Inhibitor, Isozyme-selective, Biochemical (Cat# AAA6043327)
Full Name
Akt Inhibitor, Isozyme-selective (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one; Akti-1/2)
Purity
Highly Purified
~97% (HPLC)
~97% (HPLC)
Pricing
$430/1 mg | $1,920/5x1 mg
Structure
Gedatolisib, Inhibitor (Cat# AAA577271)
Full Name
Gedatolisib (PF-05212384, PKI-587)
Purity
99.0%
Pricing
$205/2 mg | $240/5 mg | $290/10 mg | $395/25 mg | $560/50 mg | $885/100 mg | $3,710/5x100 mg
AKT2, Polyclonal Antibody (Cat# AAA1489636)
Full Name
Rabbit Anti Human AKT2 PolyClonal Antibody
Gene Names
AKT2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Affinity Purification
Pricing
$325/0.1 mL | $1,465/5x0.1 mL
Testing Data
(PI-103 is a potent, cell-permeable, ATP-competitive PI3K family members inhibitor with IC50 of 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110alpha, mTORC1, PI3-KC2beta, p110delta, mTORC2, p110beta, and p110gamma, respectively. It shows little activity against a wide array of protein kinases at 10 mM. It blocks glioma proliferation by blocking the PI 3-K/Akt pathway in vitro and in vivo. PI-103 was essentially cytostatic for cell lines and induced cell cycle arrest in the G1 phase. In blast cells, PI-103 inhibited leukemic proliferation, the clonogenicity of leukemic progenitors and induced mitochondrial apoptosis, especially in the compartment containing leukemic stem cells. PI-103 had additive proapoptotic effects with etoposide in blast cells and in immature leukemic cells. [1][2][3])
Structure
Tideglusib, Inhibitor (Cat# AAA575056)
Full Name
Tideglusib
Purity
99.84%
Pricing
$195/5 mg | $215/10 mg | $235/25 mg | $250/50 mg | $330/100 mg | $490/200 mg | $195/1 mL (in DMSO) | $1,925/5x200 mg
Structure
MTX-211, Inhibitor (Cat# AAA5750105)
Full Name
MTX-211
Purity
99.5%
Pricing
$240/1 mg | $305/2 mg | $445/5 mg | $610/10 mg | $1,080/25 mg | $1,595/50 mg | $2,250/100 mg | $445/1 mL (in DMSO) | $9,855/5x100 mg
Structure
A 769662, Inhibitor (Cat# AAA576261)
Full Name
A 769662
Purity
99.6%
Pricing
$195/2 mg | $205/5 mg | $215/10 mg | $290/25 mg | $385/50 mg | $625/100 mg | $205/1 mL (in DMSO) | $2,540/5x100 mg
Testing Data
(Jurkat cells were treated with W6000-06 at varying concentrations and assayed using Akt (Total) and [pS473] phosphoELISA. Data show effective inhibition of Akt phosphorylation using the wortmannin inhibitor.)
Wortmannin, Penicillium fumiculosum, Inhibitor (Cat# AAA655343)
Full Name
Wortmannin, Penicillium fumiculosum (PI 3-Kinase Inhibitor, KY 12420)
Purity
~98%, as assessed by TLC
Pricing
$250/10 mg | $1,120/5x10 mg
Molecular Structure
AG-1517, Inhibitor (Cat# AAA515062)
Full Name
AG-1517
Purity
99% (HPLC); NMR (Conforms)
Pricing
$195/5 mg | $380/25 mg | $1,490/5x25 mg
Structure
A66, Inhibitor (Cat# AAA575616)
Full Name
A66
Purity
99.33%
Pricing
$190/1 mg | $200/2 mg | $235/5 mg | $270/10 mg | $400/25 mg | $240/1 mL (in DMSO) | $1,530/5x25 mg
Structure
TG100-115, Inhibitor (Cat# AAA576888)
Full Name
TG100-115
Purity
99.0%
Pricing
$205/1 mg | $215/2 mg | $225/5 mg | $275/10 mg | $375/25 mg | $525/50 mg | $240/1 mL (in DMSO) | $2,100/5x50 mg
Molecular Structure
Piceatannol, Inhibitor (Cat# AAA515001)
Full Name
Piceatannol
Purity
>98% (TLC); NMR (Conforms)
Pricing
$195/5 mg | $435/25 mg | $1,735/5x25 mg
Structure
AZD-5363, Inhibitor (Cat# AAA576509)
Full Name
AZD-5363
Purity
99.48%
Pricing
$185/1 mg | $200/2 mg | $210/5 mg | $240/10 mg | $300/25 mg | $375/50 mg | $545/100 mg | $210/1 mL (in DMSO) | $2,180/5x100 mg
Structure
Antrapurol, Inhibitor (Cat# AAA577416)
Full Name
Antrapurol
Purity
98.0%
Pricing
$175/25 mg | $185/50 mg | $195/100 mg | $215/200 mg | $195/1 mL (in DMSO) | $705/5x200 mg
Structure
ETP46464, Inhibitor (Cat# AAA576593)
Full Name
ETP46464
Purity
99.56%
Pricing
$190/1 mg | $205/2 mg | $225/5 mg | $255/10 mg | $350/25 mg | $520/50 mg | $830/100 mg | $230/1 mL (in DMSO) | $3,475/5x100 mg
Structure
OTSSP167, Inhibitor (Cat# AAA576014)
Full Name
OTSSP167
Purity
98.8%
Pricing
$260/2 mg | $295/5 mg | $370/10 mg | $690/25 mg | $2,835/5x25 mg
Structure
BYL-719, Inhibitor (Cat# AAA576012)
Full Name
BYL-719(Alpelisib)
Purity
99.25%
Pricing
$185/1 mg | $195/2 mg | $205/5 mg | $215/10 mg | $235/25 mg | $240/50 mg | $290/100 mg | $745/500 mg | $395/200 mg | $205/1 mL (in DMSO) | $3,085/5x500 mg
Structure
Torkinib, Inhibitor (Cat# AAA576137)
Full Name
Torkinib (PP242)
Purity
99.23%
Pricing
$185/2 mg | $200/5 mg | $215/10 mg | $255/25 mg | $270/50 mg | $345/100 mg | $450/200 mg | $200/1 mL (in DMSO) | $1,750/5x200 mg
Testing Data
(PP121 is a multitargeted dual receptor tyrosine kinases inhibitor with IC50 of 0.052, 1.4, 0.15, 1.1, 0.06, 0.01and 0.002 uM for p110alpha, p110beta, p110delta, p110gamma, DNA-PK, mTOR and PDGFR, respectively. PP121 also inhibits Abl, Hck, Src,Src(T338I), VEGFR2, EGFR EphB4 with IC50 of 0.018, 0.008, 0.014, 0.22, 0.012, 0.26, 0.19 uM, respectively. PP121 exhibits no significant effect on receptor serine/threonine kinases (RSTKs). PP121 blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor. PP121 achieves its dual potency by targeting a residue (Glu310 in Src) that has been structurally conserved between kinase families. PP121 potently and dose-dependently blocked the phosphorylation of Akt, p70S6K and S6 in these cells. [1])
