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Secretogranin 3 Recombinant Protein | SCG3 recombinant protein
Secretogranin 3 Protein, Mouse, Recombinant (His Tag)
Gene Names
Scg3; Chgd; SgIII; 1B1075; AI385542
Purity
>95% as determined by SDS-PAGE
Synonyms
Secretogranin 3; Secretogranin 3 Protein; Mouse; Recombinant (His Tag); Mouse SCG3/Secretogranin 3 Protein (His Tag); 1B1075 Protein; AI385542 Protein; Chgd Protein; SgIII Protein; secretogranin III; SCG3 recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Leu471
Species
Mouse
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Phe 23
Tag
C-His
Protein Construction
A DNA sequence encoding the mouse Scg3 (NP_033156.1)(Met1-Leu471) was expressed with a polyhistidine tag at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for SCG3 recombinant protein
Background: SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) in neuroendocrine cells. SCG3 binds strongly to chromogranin A (CgA) in an intragranular milieu and targets CgA to SGs in pituitary and pancreatic endocrine cells. With a sucrose density gradient of rat insulinoma-derived INS-1 cell homogenates, SgIII is localized to the SG fraction and is fractionated to the SG membrane (SGM) despite lacking the transmembrane region.
References
Rong YP. et al., 2002, Sheng Wu Wu Li Xue Bao. 34 (4): 411-7.Huttner WB. et al., 1991, Trends Biochem Sci. 16 (1): 27-30.Ozawa H. et al., 1996, Cell Struct Funct. 20 (6): 415-20.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,784 Da
NCBI Official Full Name
secretogranin-3 isoform 1
NCBI Official Synonym Full Names
secretogranin III
NCBI Official Symbol
Scg3
NCBI Official Synonym Symbols
Chgd; SgIII; 1B1075; AI385542
NCBI Protein Information
secretogranin-3
UniProt Protein Name
Secretogranin-3
Protein Family
UniProt Gene Name
Scg3
UniProt Synonym Gene Names
SgIII
UniProt Entry Name
SCG3_MOUSE
Uniprot Description
SCG3: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: membrane; extracellular region; cytoplasmic vesicle
Research Articles on SCG3
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Product Notes
The SCG3 scg3 (Catalog #AAA8123220) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Leu47 1. It is sometimes possible for the material contained within the vial of "Secretogranin 3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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