Protein transport protein SBH1 (SBH1) Recombinant Protein | SBH1 recombinant protein

Recombinant Saccharomyces cerevisiae Protein transport protein SBH1 (SBH1), partial

Cat. Num. AAA1221604

• Gene Names: SBH1; SEB1; YER087C-A
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Protein transport protein SBH1 (SBH1); Recombinant Saccharomyces cerevisiae Protein transport protein SBH1 (SBH1); partial; SBH1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-53
• Sequence: MSSPTPPGGQ RTLQKRKQGS SQKVAASAPK KNTNSNNSIL KIYSDEATGL RVD
• Sequence Length: 53

• Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 398364575
• NCBI GeneID: 856821
• NCBI Accession #: NP_011011.3
• NCBI GenBank Nucleotide #: NM_001180032.3
• UniProt Accession #: P52870; D3DLZ4
• Molecular Weight: 8,711 Da
• NCBI Official Full Name: Arf family guanine nucleotide exchange factor SBH1
• NCBI Official Symbol: SBH1
• NCBI Official Synonym Symbols: SEB1; YER087C-A
• NCBI Protein Information: Arf family guanine nucleotide exchange factor SBH1
• UniProt Protein Name: Protein transport protein SBH1
• Protein Family: Protein transport protein
• UniProt Gene Name: SBH1
• UniProt Synonym Gene Names: SEB1

Uniprot Description

Part of the Sec61 complex, which is the major component of a channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). The functional states of the translocon complex include co- and post-translational ER import, cotranslational membrane protein integration and retrograde transport of misfolded proteins out of the ER. In the cotranslational pathway, ribosomes synthesizing presecretory proteins are targeted to the translocon by the cytosolic signal recognition particle (SRP) and its ER-localized receptor. The association of the Sec61 complex with the ribosome is mediated by the 28S rRNA of the large ribosomal subunit. SRP-independent post-translational translocation requires the association of additional factors, such as the Sec62/63 complex and KAR2.