Mouse Ras-related associated with diabetes ELISA Kit | RRAD elisa kit
Mouse GTP-binding protein RAD, RRAD ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
RRAD: a small G protein of the RGK family. May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Interacts with calmodulin preferentially in the inactive, GDP-bound form. Interacts with CAMK2D and CACNB2. Interaction with CACNB2 regulates the trafficking of CACNA1C to the cell membrane. Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
Protein type: G protein, monomeric; G protein, monomeric, RGK; G protein
Cellular Component: membrane; plasma membrane
Molecular Function: calmodulin binding; protein binding; GTP binding; nucleotide binding
Biological Process: small GTPase mediated signal transduction; negative regulation of cell growth; signal transduction
Research Articles on RRAD
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Product Notes
The Mouse RRAD rrad (Catalog #AAA9325666) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325666 ELISA Kit recognizes Mouse RRAD. It is sometimes possible for the material contained within the vial of "Ras-related associated with diabetes, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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