Interleukin 3 Active Protein | IL3 active protein

Interleukin 3, Recombinant, Human (IL-3)

Cat. Num. AAA650960

• Gene Names: IL3; IL-3; MCGF; MGC79398; MGC79399; MULTI-CSF
• Purity: Highly Purified; 98% by SDS-PAGE and HPLC analyses. Endotoxin: 0.1ng/ug (1EU/ug).
• Synonyms: Interleukin 3; Recombinant; Human (IL-3); IL3 active protein

• Host: Recombinant, Human (E Coli).
• Purity/Purification: Highly Purified; 98% by SDS-PAGE and HPLC analyses. Endotoxin: 0.1ng/ug (1EU/ug).
• Form/Format: Supplied as a lyophilized protein with no additives.

• Biological Activity: Human IL-3 is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of TF-1 cells is < 0.1 ng/ml, corresponding to a specific activity of > 1.0x10e7 units/mg.
• Country of Origin: USA
• Preparation and Storage: Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile ddH2O, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer

Related Product Information for IL3 active protein

Interleukin-3 (IL-3) is a species specific colony stimulating factor which stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. Human IL-3 is a 15.0kDa protein containing 133 amino acid residues.

Product Categories/Family for IL3 active protein

Growth Factors; Cytokines; Growth Factors-Interleukin

NCBI and Uniprot Product Information

• NCBI GI #: 28416915
• NCBI GeneID: 3562
• NCBI Accession #: NP_000579.2
• NCBI GenBank Nucleotide #: NM_000588.3
• UniProt Accession #: P08700; Q6GS87; Q6NZ78; Q6NZ79
• Molecular Weight: 15.0kD
• NCBI Official Full Name: interleukin-3
• NCBI Official Synonym Full Names: interleukin 3 (colony-stimulating factor, multiple)
• NCBI Official Symbol: IL3
• NCBI Official Synonym Symbols: IL-3; MCGF; MGC79398; MGC79399; MULTI-CSF
• NCBI Protein Information: interleukin-3; OTTHUMP00000065963; mast cell growth factor; mast-cell growth factor; P-cell stimulating factor; P-cell-stimulating factor; hematopoietic growth factor; multilineage-colony-stimulating factor; multipotential colony-stimulating factor
• UniProt Protein Name: Interleukin-3
• Protein Family: Interleukin
• UniProt Gene Name: IL3
• UniProt Entry Name: IL3_HUMAN

NCBI Description

The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq]

Uniprot Description

Function: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.

Subunit structure: Monomer.

Subcellular location: Secreted.

Tissue specificity: Activated T-cells, mast cells, natural killer cells.

Sequence similarities: Belongs to the IL-3 family.