Rat TRIM63/E3 Ubiquitin-Protein Ligase TRIM63 ELISA Kit | TRIM63 elisa kit
Rat TRIM63/E3 Ubiquitin-Protein Ligase TRIM63 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
ubiquitin ligase that is upregulated in models of muscle atrophy; may facilitate protein degradation and skeletal muscle atrophy [RGD, Feb 2006]
Uniprot Description
Function: E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.2 PublicationsManual assertion based on experiment in:Ref.1
Research Articles on TRIM63
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Product Notes
The Rat TRIM63 trim63 (Catalog #AAA2890952) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2890952 ELISA Kit recognizes Rat TRIM63. It is sometimes possible for the material contained within the vial of "TRIM63/E3 Ubiquitin-Protein Ligase TRIM63, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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