Typical Testing Data/Standard Curve (for reference only)
Rat ApoA2 (Apolipoprotein A2) CLIA Kit | ApoA2 clia kit
Rat ApoA2 (Apolipoprotein A2) CLIA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to ApoA2. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for ApoA2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain ApoA2, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of ApoA2. You can calculate the concentration of ApoA2 in the samples by comparing the RLU value of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
Uniprot Description
APOA2: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Belongs to the apolipoprotein A2 family.
Protein type: Secreted; Endoplasmic reticulum; Lipid-binding; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q23.3
Cellular Component: chylomicron; cytosol; early endosome; endoplasmic reticulum lumen; extracellular region
Molecular Function: apolipoprotein receptor binding; cholesterol binding; cholesterol transporter activity; high-density lipoprotein binding; lipase inhibitor activity; lipid binding; lipid transporter activity; phosphatidylcholine binding; phospholipid binding; protein binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: acute inflammatory response; cellular lipid metabolic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; diacylglycerol catabolic process; fat-soluble vitamin metabolic process; lipoprotein metabolic process; negative regulation of cholesterol transport; negative regulation of cytokine secretion during immune response; negative regulation of lipase activity; negative regulation of lipid catabolic process; organ regeneration; peptidyl-methionine modification; phosphatidylcholine biosynthetic process; phospholipid catabolic process; phospholipid efflux; phototransduction, visible light; positive regulation of catalytic activity; positive regulation of interleukin-8 biosynthetic process; positive regulation of lipid catabolic process; protein amino acid oxidation; protein folding; regulation of cholesterol absorption; regulation of protein stability; response to drug; response to estrogen stimulus; response to glucocorticoid stimulus; response to glucose stimulus; retinoid metabolic process; reverse cholesterol transport; triacylglycerol metabolic process; viral reproduction; vitamin metabolic process
Disease: Hypercholesterolemia, Familial
Research Articles on ApoA2
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Product Notes
The Rat ApoA2 apoa2 (Catalog #AAA2530486) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2530486 CLIA Kit recognizes Rat ApoA2. It is sometimes possible for the material contained within the vial of "ApoA2 (Apolipoprotein A2), CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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