Typical Testing Data/Standard Curve
Mouse TIG2 ELISA Kit | RARRES2 elisa kit
Mouse TIG2 ELISA Kit
Gene Names
Rarres2; AI303516; 0610007L05Rik
Reactivity
Mouse
Applications
ELISA
Synonyms
TIG2; Mouse TIG2 ELISA Kit; Retinoic acid receptor responder protein 2; Chemerin; RAR-responsive protein TIG2; Tazarotene-induced gene 2 protein; RARRES2 elisa kit
Reactivity
Mouse
Specificity
The Mouse TIG2 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse TIG2 proteins within the range of 780 pg/ml - 50000 pg/ml.
Sequence Length
162
Applicable Applications for RARRES2 elisa kit
Sandwich ELISA (EIA)
Samples
Cell Culture Supernatants, Serum, Plasma.
Sensitivity
20 pg/ml.
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Typical Testing Data/Standard Curve
Typical Testing Data/Standard Curve
Related Product Information for RARRES2 elisa kit
Principle of the Assay||The Mouse TIG2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse TIG2 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Mouse TIG2 coated on a 96-well plate. Standards and samples are pipetted into the wells and TIG2 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse TIG2 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of TIG2 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background/Introduction: Chemerin, also known as RARRES2 or TIG2, is a protein that in humans is encoded by the RARRES2 gene. It is mapped to 7q36.1. Chemerin is a potent chemoattractant specific for antigen-presenting cells that requires proteolytic activation and acts as a ligand for the G protein-coupled receptor CMKLR1 (also known as ChemR23). It is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. What's more, the active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.
Background/Introduction: Chemerin, also known as RARRES2 or TIG2, is a protein that in humans is encoded by the RARRES2 gene. It is mapped to 7q36.1. Chemerin is a potent chemoattractant specific for antigen-presenting cells that requires proteolytic activation and acts as a ligand for the G protein-coupled receptor CMKLR1 (also known as ChemR23). It is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. What's more, the active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
18,350 Da
NCBI Official Full Name
Retinoic acid receptor responder protein 2
NCBI Official Synonym Full Names
retinoic acid receptor responder (tazarotene induced) 2
NCBI Official Symbol
Rarres2
NCBI Official Synonym Symbols
AI303516; 0610007L05Rik
NCBI Protein Information
retinoic acid receptor responder protein 2
UniProt Protein Name
Retinoic acid receptor responder protein 2
Protein Family
UniProt Gene Name
Rarres2
UniProt Entry Name
RARR2_MOUSE
Uniprot Description
RARRES2: Inhibited in psoriatic lesions. Activated by tazarotene in skin rafts and in the epidermis of psoriatic lesions.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular matrix; extracellular region
Molecular Function: protein binding; receptor binding
Biological Process: brown fat cell differentiation; cell differentiation; chemotaxis; defense response; embryonic gut development; inflammatory response; positive regulation of chemotaxis; positive regulation of fat cell differentiation; positive regulation of protein amino acid phosphorylation; regulation of lipid catabolic process; retinoid metabolic process
Research Articles on RARRES2
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Product Notes
The Mouse RARRES2 rarres2 (Catalog #AAA8244606) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8244606 ELISA Kit recognizes Mouse RARRES2. AAA Biotech's TIG2 can be used in a range of immunoassay formats including, but not limited to, Sandwich ELISA (EIA). Researchers should empirically determine the suitability of the RARRES2 rarres2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIG2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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