NKG2D ligand 4 (RAET1E) Recombinant Protein | RAET1E recombinant protein

Recombinant Human NKG2D ligand 4 (RAET1E), partial

Cat. Num. AAA1449463

• Gene Names: RAET1E; RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: NKG2D ligand 4 (RAET1E); Recombinant Human NKG2D ligand 4 (RAET1E); partial; RAET1E recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 31-225
• Sequence: HSLCFNFTIK SLSRPGQPWC EAQVFLNKNL FLQYNSDNNM VKPLGLLGKK VYATSTWGEL TQTLGEVGRD LRMLLCDIKP QIKTSDPSTL QVEMFCQREA ERCTGASWQF ATNGEKSLLF DAMNMTWTVI NHEASKIKET WKKDRGLEKY FRKLSKGDCD HWLREFLGHW EAMPEPTVSP VNASDIHWSS SSLPD
• Sequence Length: 195

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 343183381
• NCBI GeneID: 135250
• NCBI Accession #: NP_001230254.1
• NCBI GenBank Nucleotide #: NM_001243325.1
• UniProt Accession #: Q8TD07; Q5VYB7; Q5VYB8; Q8TEZ2; Q96L41; A6YF59
• Molecular Weight: 32,300 Da
• NCBI Official Full Name: retinoic acid early transcript 1E isoform 2
• NCBI Official Synonym Full Names: retinoic acid early transcript 1E
• NCBI Official Symbol: RAET1E
• NCBI Official Synonym Symbols: RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7
• NCBI Protein Information: retinoic acid early transcript 1E; NKG2D ligand 4
• UniProt Protein Name: Retinoic acid early transcript 1E
• Protein Family: NKG2D ligand
• UniProt Gene Name: RAET1E
• UniProt Synonym Gene Names: N2DL-4; NKG2DL4

NCBI Description

This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]

Uniprot Description

Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.