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Western Blot (WB) (Western blot analysis UNC5A using Jurkat whole cell lysates)

Rabbit UNC5A Antibody | anti-UNC5A antibody

UNC5A Antibody

Gene Names
UNC5A; UNC5H1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antibody was Affinity-Purified from rabbit antiserum by Affinity-Chromatography using epitope-specific immunogen.
Synonyms
UNC5A; UNC5A Antibody; anti-UNC5A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
UNC5A Polyclonal Antibody detects endogenous levels of protein.
Purity/Purification
The antibody was Affinity-Purified from rabbit antiserum by Affinity-Chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
842
Applicable Applications for anti-UNC5A antibody
Western Blot (WB), ELISA
Application Notes
WB: 1:500-2000
ELISA: 1:5000-1:20000
Immunogen
Synthesized peptide derived from human protein at AA range: 130-210
Preparation and Storage
Store at -20°C for 1 year.

Western Blot (WB)

(Western blot analysis UNC5A using Jurkat whole cell lysates)

Western Blot (WB) (Western blot analysis UNC5A using Jurkat whole cell lysates)
Related Product Information for anti-UNC5A antibody
Background: unc-s netrin receptor A (UNCSA) Homo sapiens UNCSA belongs to a family of netrin-1 (MlM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNCS proteins, see UNC5c (MIM 603610). [supplied by OMIM, Apr 2004], Function: domain: The ZUS domain mediates the interaction with MAGED1, which participates in the induction of apoptosis. Function: Receptor for netrin required for axon guidance.

Expression: Brain, PCR rescued clones, Pooled,

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed Band (KD): 92
NCBI Official Full Name
netrin receptor UNC5A
NCBI Official Synonym Full Names
unc-5 netrin receptor A
NCBI Official Symbol
UNC5A
NCBI Official Synonym Symbols
UNC5H1
NCBI Protein Information
netrin receptor UNC5A
UniProt Protein Name
Netrin receptor UNC5A
Protein Family
UniProt Gene Name
UNC5A
UniProt Synonym Gene Names
KIAA1976; UNC5H1

NCBI Description

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM, Apr 2004]

Uniprot Description

Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.

Research Articles on UNC5A

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Product Notes

The UNC5A unc5a (Catalog #AAA8518689) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UNC5A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's UNC5A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA. WB: 1:500-2000 ELISA: 1:5000-1:20000. Researchers should empirically determine the suitability of the UNC5A unc5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UNC5A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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