Western Blot (WB)
(Western blot analysis of extracts of HeLa cells, using FOLR1 antibody. Secondary antibody: HRP Goat Anti-Rabbit IgG (H + L) at 1: 10000 dilution. Lysates / proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.)
Rabbit anti-Human FOLR1 Antibody | anti-FOLR1 antibody
FOLR1 Polyclonal Antibody
Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of HeLa cells, using FOLR1 antibody. Secondary antibody: HRP Goat Anti-Rabbit IgG (H + L) at 1: 10000 dilution. Lysates / proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.)
Western Blot (WB)
(Western blot analysis of extracts of HeLa cells, using FOLR1 antibody. Secondary antibody: HRP Goat Anti-Rabbit IgG (H + L) at 1: 10000 dilution. Lysates / proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
Uniprot Description
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Research Articles on FOLR1
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Product Notes
The FOLR1 folr1 (Catalog #AAA8503555) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOLR1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FOLR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB 1:500-1:1000; IHC 1:50-1:100; FC 1:20-1:50. Researchers should empirically determine the suitability of the FOLR1 folr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOLR1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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