Ras-related protein Rab-8A (RAB8A) Recombinant Protein | RAB8A recombinant protein
Recombinant Chicken Ras-related protein Rab-8A (RAB8A)
GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB
YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP
GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB
YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
NCBI and Uniprot Product Information
Uniprot Description
May be involved in vesicular trafficking and neurotransmitter release.
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Product Notes
The RAB8A rab8a (Catalog #AAA1317074) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-204, Full length protein. The amino acid sequence is listed below: MAKTYDYLFK LLLIGDSGVG KTCALFRFSE DAFNATFIST IGIDFKIRTI ELDGKRIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFENIR NWVRNIEEHA SPDVEKMILG NKCDANDKRQ VSREQGEKLA ASFGIKFMET SAKANINIEN AFFTLARDIK AKMDKKLEGN SPQGSNQGVK ITPDQQKKSS FFRC. It is sometimes possible for the material contained within the vial of "Ras-related protein Rab-8A (RAB8A), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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