Mouse PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) ELISA Kit | PRPF8 elisa kit
Mouse Pre-mRNA-processing-splicing factor 8, PRPF8 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PRPF8: Central component of the spliceosome, which may play a role in aligning the pre-mRNA 5'- and 3'-exons for ligation. Interacts with U5 snRNA, and with pre-mRNA 5'-splice sites in B spliceosomes and 3'-splice sites in C spliceosomes. Defects in PRPF8 are the cause of retinitis pigmentosa type 13 (RP13). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP13 inheritance is autosomal dominant.
Protein type: RNA splicing; Spliceosome; RNA-binding
Cellular Component: spliceosome; membrane; snRNP U5; ribonucleoprotein complex; nucleus
Molecular Function: U5 snRNA binding; nucleic acid binding; RNA binding; U6 snRNA binding
Biological Process: assembly of spliceosomal tri-snRNP; nuclear mRNA splicing, via spliceosome; RNA splicing; mRNA processing
Research Articles on PRPF8
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Product Notes
The Mouse PRPF8 prpf8 (Catalog #AAA9326062) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9326062 ELISA Kit recognizes Mouse PRPF8. It is sometimes possible for the material contained within the vial of "PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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