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Trypsin inhibitor Protein | ITIH2 protein

Soybean Trypsin inhibitor

Synonyms
Trypsin inhibitor; Soybean Trypsin inhibitor; Immobilized Soybean Trypsin Inhibitor; ITIH2 protein
Ordering
For Research Use Only!
Form/Format
This presentation immobilized SBTI is on an agarose resin via coupling to primary amines. This creates an affinity resin with specificity for a number of serine proteases. Detail as follows: -Resin Matix: Affi-Gel 10 -Attachement: Amino -Ligand Density: 1
Sequence Length
946
Storage Buffer
0.1 M Tris; 0.05 M NaCl; 0.1% Sodium Azide; pH 7.5
Isoelectric Point
4.51,2
Preparation and Storage
At -70 degree C
Related Product Information for ITIH2 protein
Description: Soybean trypsin inhibitor (SBTI) is a reversible competitive inhibitor of trypsin and other trypsin-like proteases such as chymotrypsin, plasmin and plasma kallikrein. This presentation of SBTI binds free trypsin tightly with high pH (4.5-8.0) and allows for a simple gradient to low pH (~2.5-3.0) for elution
References
1. Birk, Y. (1976) Methods Enzymol. 55:700-70
6.
2. Kassell, B. (1970) Methods Enzymol. 19:853-862.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
22 kDa1,2
NCBI Official Full Name
trypsin inhibitor
UniProt Protein Name
Inter-alpha-trypsin inhibitor heavy chain H2
Protein Family
UniProt Gene Name
ITIH2
UniProt Synonym Gene Names
IGHEP2; ITI heavy chain H2; ITI-HC2; Inter-alpha-inhibitor heavy chain 2; SHAP
UniProt Entry Name
ITIH2_HUMAN

Uniprot Description

ITIH2: May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Belongs to the ITIH family.

Protein type: Secreted; Inhibitor; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10p15

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity

Biological Process: hyaluronan metabolic process

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Product Notes

The Trypsin inhibitor itih2 (Catalog #AAA480770) is a Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Trypsin inhibitor, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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