Galanin (GAL) Small Molecule | GAL small molecule

OVA Conjugated Galanin (GAL)

Cat. Num. AAA2086426

• Gene Names: GAL; ETL8; GALN; GLNN; GMAP; GAL-GMAP
• Applications: SDS-Page, Western Blot
• Purity: > 90%
• Synonyms: Galanin (GAL); OVA Conjugated Galanin (GAL); GALN; GLNN; GMAP; Galanin Prepropeptide; Galanin-Message-Associated Peptide; GAL small molecule

• Host: Protein Conjugation
• Purity/Purification: > 90%
• Form/Format: Freeze-dried powder
• Sequence Length: 123

• Applicable Applications for GAL small molecule: Immunogen, SDS-PAGE, Western Blot (WB)
• Buffer Formulation: PBS, pH7.4.
• Organism Species: Human
• Usage: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Sequence Information

SDS-Page

Testing Data

Testing Data

Product Categories/Family for GAL small molecule

Conjugated small molecules

NCBI and Uniprot Product Information

• NCBI GI #: 27804313
• NCBI GeneID: 51083
• NCBI Accession #: NP_057057.2
• NCBI GenBank Nucleotide #: NM_015973.4
• UniProt Accession #: P22466; Q14413
• Molecular Weight: 13,302 Da
• NCBI Official Full Name: galanin peptides preproprotein
• NCBI Official Synonym Full Names: galanin and GMAP prepropeptide
• NCBI Official Symbol: GAL
• NCBI Official Synonym Symbols: ETL8; GALN; GLNN; GMAP; GAL-GMAP
• NCBI Protein Information: galanin peptides
• UniProt Protein Name: Galanin peptides
• Protein Family: Galanin
• UniProt Gene Name: GAL
• UniProt Synonym Gene Names: GAL1; GALN; GLNN; GMAP

NCBI Description

This gene encodes a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP). Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation and water balance. GMAP has been demonstrated to possess antifungal activity and hypothesized to be part of the innate immune system. [provided by RefSeq, Jul 2015]

Uniprot Description

Galanin: Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion. Belongs to the galanin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: cell soma; extracellular region; extracellular space; secretory granule

Molecular Function: galanin receptor activity; neuropeptide hormone activity; protein binding; type 1 galanin receptor binding; type 2 galanin receptor binding; type 3 galanin receptor binding

Biological Process: cAMP-mediated signaling; positive regulation of catagen; positive regulation of cortisol secretion; positive regulation of transcription from RNA polymerase II promoter

Disease: Epilepsy, Familial Temporal Lobe, 8