SDS-PAGE
Peroxiredoxin 1 / PRDX1 Recombinant Protein | PRDX1 recombinant protein
Recombinant Mouse Peroxiredoxin 1 / PRDX1 Protein (His tag)
SDS-PAGE
SDS-PAGE
Description: A DNA sequence encoding the mouse PRDX1 (P35700) (Met 1-Lys 199) was expressed, with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
Uniprot Description
PRDX1: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression.
Protein type: EC 1.11.1.15; Nuclear receptor co-regulator; Oxidoreductase
Chromosomal Location of Human Ortholog: 4 D1|4 53.28 cM
Cellular Component: cell-cell adherens junction; cytoplasm; cytosol; extracellular matrix; extracellular space; mitochondrial matrix; mitochondrion; myelin sheath; nucleolus; nucleus; peroxisomal matrix
Molecular Function: heme binding; peroxidase activity; peroxiredoxin activity; protein homodimerization activity; thioredoxin peroxidase activity
Biological Process: cell proliferation; erythrocyte homeostasis; hydrogen peroxide catabolic process; natural killer cell mediated cytotoxicity; regulation of NF-kappaB import into nucleus; regulation of stress-activated MAPK cascade; removal of superoxide radicals; response to oxidative stress; response to reactive oxygen species
Research Articles on PRDX1
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Product Notes
The PRDX1 prdx1 (Catalog #AAA2546919) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse PRDX1 comprises 209 amino acids and has a calculated molecular mass of 23.5 kDa. The recombinant protein migrates as an approximately 27 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the PRDX1 prdx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peroxiredoxin 1 / PRDX1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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