Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Typical Testing Data/Standard Curve (for reference only) (Fig.1. Mouse Peroxiredoxin-1 (PRDX1) Standard Curve.)

Mouse Peroxiredoxin-1 (PRDX1) ELISA Kit | PRDX1 elisa kit

Mouse Peroxiredoxin-1 (PRDX1) ELISA Kit

Gene Names
Prdx1; PAG; OSF3; Paga; PrxI; TDX2; TPxA; prx1; MSP23; NkefA; OSF-3; PrdxI; Tdpx2
Reactivity
Mouse
Synonyms
Peroxiredoxin-1 (PRDX1); Mouse Peroxiredoxin-1 (PRDX1) ELISA Kit; PRDX1; MSP23; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2; natural killer-enhancing factor A; proliferation-associated gene A; thioredoxin-dependent peroxide reductase 2; PRDX1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
Mouse Peroxiredoxin-1 (PRDX1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PRDX1. No significant cross-reactivity or interference between Mouse PRDX1 and analogues was observed.
Sequence Length
199
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

(Fig.1. Mouse Peroxiredoxin-1 (PRDX1) Standard Curve.)

Typical Testing Data/Standard Curve (for reference only) (Fig.1. Mouse Peroxiredoxin-1 (PRDX1) Standard Curve.)
Related Product Information for PRDX1 elisa kit
Description: This Mouse Peroxiredoxin-1 (PRDX1) ELISA Kit employs a two-site sandwich ELISA to quantitate PRDX1 in samples. An antibody specific for PRDX1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PRDX1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PRDX1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PRDX1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Background: Peroxiredoxin-1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
peroxiredoxin-1
NCBI Official Synonym Full Names
peroxiredoxin 1
NCBI Official Symbol
Prdx1
NCBI Official Synonym Symbols
PAG; OSF3; Paga; PrxI; TDX2; TPxA; prx1; MSP23; NkefA; OSF-3; PrdxI; Tdpx2
NCBI Protein Information
peroxiredoxin-1
UniProt Protein Name
Peroxiredoxin-1
Protein Family
UniProt Gene Name
Prdx1
UniProt Synonym Gene Names
Msp23; Paga; Tdpx2; OSF-3

Uniprot Description

PRDX1: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression.

Protein type: EC 1.11.1.15; Nuclear receptor co-regulator; Oxidoreductase

Chromosomal Location of Human Ortholog: 4 D1|4 53.28 cM

Cellular Component: cell-cell adherens junction; cytoplasm; cytosol; extracellular matrix; extracellular space; mitochondrial matrix; mitochondrion; myelin sheath; nucleolus; nucleus; peroxisomal matrix

Molecular Function: heme binding; peroxidase activity; peroxiredoxin activity; protein homodimerization activity; thioredoxin peroxidase activity

Biological Process: cell proliferation; erythrocyte homeostasis; hydrogen peroxide catabolic process; natural killer cell mediated cytotoxicity; regulation of NF-kappaB import into nucleus; regulation of stress-activated MAPK cascade; removal of superoxide radicals; response to oxidative stress; response to reactive oxygen species

Research Articles on PRDX1

Similar Products

Product Notes

The Mouse PRDX1 prdx1 (Catalog #AAA9718044) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9718044 ELISA Kit recognizes Mouse PRDX1. It is sometimes possible for the material contained within the vial of "Peroxiredoxin-1 (PRDX1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.