Human phosphatidic acid phosphatase type 2C ELISA Kit | PPAP2C elisa kit
Human Lipid phosphate phosphohydrolase 2, PPAP2C ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Uniprot Description
PPAP2C: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. Belongs to the PA-phosphatase related phosphoesterase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; Motility/polarity/chemotaxis; Phosphatase, lipid; EC 3.1.3.4; Lipid Metabolism - sphingolipid; Lipid Metabolism - glycerolipid; Lipid Metabolism - ether lipid
Chromosomal Location of Human Ortholog: 19p13
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: phosphatidate phosphatase activity; phosphoprotein phosphatase activity
Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; dephosphorylation
Research Articles on PPAP2C
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Product Notes
The Human PPAP2C ppap2c (Catalog #AAA9324582) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9324582 ELISA Kit recognizes Human PPAP2C. It is sometimes possible for the material contained within the vial of "phosphatidic acid phosphatase type 2C, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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