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Lipid phosphate phosphohydrolase 1 (PPAP2A) Recombinant Protein | PPAP2A recombinant protein

Recombinant Pig Lipid phosphate phosphohydrolase 1 (PPAP2A)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Lipid phosphate phosphohydrolase 1 (PPAP2A); Recombinant Pig Lipid phosphate phosphohydrolase 1 (PPAP2A); Recombinant Lipid phosphate phosphohydrolase 1 (PPAP2A); Lipid phosphate phosphohydrolase 1 EC= 3.1.3.4; PAP2-alpha Phosphatidate phosphohydrolase type 2a Phosphatidic acid phosphatase 2a; PAP-2a; PAP2a; PPAP2A recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-15aa; Full length protein
Sequence
MFDKTRLPYV ALDVL
Sequence Length
15
Species
Sus scrofa (Pig)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for PPAP2A recombinant protein
This protein is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
1,781 Da
NCBI Official Full Name
Lipid phosphate phosphohydrolase 1
UniProt Protein Name
Lipid phosphate phosphohydrolase 1
UniProt Gene Name
PPAP2A
UniProt Synonym Gene Names
LPP1; PAP-2a; PAP2a
UniProt Entry Name
LPP1_PIG

Uniprot Description

Function: Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), diacyl glycerol pyrophosphate (DGPP), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P).

Catalytic activity: A 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.

Subunit structure: Homodimer

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the PA-phosphatase related phosphoesterase family.

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Product Notes

The Lipid phosphate phosphohydrolase 1 (PPAP2A) ppap2a (Catalog #AAA960679) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-15aa; Full length protein. The amino acid sequence is listed below: MFDKTRLPYV ALDVL. It is sometimes possible for the material contained within the vial of "Lipid phosphate phosphohydrolase 1 (PPAP2A), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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