Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ZZZ3 Polyclonal Antibody at dilution of 1:50(×200))
Rabbit anti-Human, Mouse ZZZ3 Polyclonal Antibody | anti-ZZZ3 antibody
ZZZ3 Polyclonal Antibody
Gene Names
ZZZ3; ATAC1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
ZZZ3; Polyclonal Antibody; ZZZ3 Polyclonal Antibody; ATAC component 1 homolog; ATAC1; DKFZp313N0119; DKFZp564I052; FLJ10362; Zinc finger ZZ domain containing 3; Zinc finger ZZ type containing 3; ZZ type zinc finger containing protein 3; ZZ-type zinc finger-containing protein 3; ZZZ 3; anti-ZZZ3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.8mg/mL (varies by lot)
Sequence Length
903
Applicable Applications for anti-ZZZ3 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:40-1:250
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human ZZZ3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ZZZ3 Polyclonal Antibody at dilution of 1:50(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ZZZ3 Polyclonal Antibody at dilution of 1:50(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using ZZZ3 Polyclonal Antibody at dilution of 1:50(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using ZZZ3 Polyclonal Antibody at dilution of 1:50(×200))
Related Product Information for anti-ZZZ3 antibody
ZZZ3 (ZZ-type zinc finger-containing protein 3) is a 903 amino acid protein that contains one HTH myb-type DNA-binding domain and one ZZ-type zinc finger. Phosphorylated upon DNA damage by ATM or ATR, ZZZ3 is a subunit of the ATAC complex, which is composed of GCN5, CRP2BP, ADA3, TADA2L, DR1, CCDC101, YEATS2, WDR5 and MBIP. The ATAC complex has histone acetyltransferase activity on histones H3 and H4. ZZZ3 is expressed as four isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3, 000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Product Categories/Family for anti-ZZZ3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
ZZ-type zinc finger-containing protein 3 isoform 1
NCBI Official Synonym Full Names
zinc finger ZZ-type containing 3
NCBI Official Symbol
ZZZ3
NCBI Official Synonym Symbols
ATAC1
NCBI Protein Information
ZZ-type zinc finger-containing protein 3
UniProt Protein Name
ZZ-type zinc finger-containing protein 3
Protein Family
UniProt Gene Name
ZZZ3
UniProt Entry Name
ZZZ3_HUMAN
Uniprot Description
ZZZ3: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1p31.1
Cellular Component: nuclear membrane; nucleolus; nucleus
Molecular Function: protein binding; DNA binding; zinc ion binding; chromatin binding
Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on ZZZ3
Similar Products
Product Notes
The ZZZ3 zzz3 (Catalog #AAA2560366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZZZ3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZZZ3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:40-1:250 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the ZZZ3 zzz3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZZZ3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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