Western Blot (WB)
(WB Suggested Anti-ZNF280B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 293T cell lysate)
Rabbit ZNF280B Polyclonal Antibody | anti-ZNF280B antibody
ZNF280B antibody - C-terminal region
Gene Names
ZNF280B; SUHW2; ZNF279; ZNF632; 5'OY11.1; D87009.C22.3
Reactivity
Cow, Dog, Human, Pig
Applications
Western Blot
Purity
Affinity Purified
Synonyms
ZNF280B; Polyclonal Antibody; ZNF280B antibody - C-terminal region; anti-ZNF280B antibody
Host
Rabbit
Reactivity
Cow, Dog, Human, Pig
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: PPETKVTIQVSLEPLQPGSVDVASITVSTSDSEPSLPRSKSKISKKSH
Sequence Length
543
Applicable Applications for anti-ZNF280B antibody
Western Blot (WB)
Homology
Cow: 92%; Dog: 92%; Human: 100%; Pig: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF280B
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-ZNF280B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 293T cell lysate)
Western Blot (WB)
(WB Suggested Anti-ZNF280B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 293T cell lysate)
Related Product Information for anti-ZNF280B antibody
This is a rabbit polyclonal antibody against ZNF280B. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: ZNF280B contains 4 C2H2-type zinc fingers. It may function as a transcription factor.This gene was identified by homology to other species. Its encoded protein is approximately 78-88% identical to a predicted sheep protein of unknown function. The protein is also approximately 25% identical to the Drosophila protein suppressor of hairy wing, which is a leucine zipper protein that represses the function of transcriptional enhancers of the gypsy retrotransposon. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
Target Description: ZNF280B contains 4 C2H2-type zinc fingers. It may function as a transcription factor.This gene was identified by homology to other species. Its encoded protein is approximately 78-88% identical to a predicted sheep protein of unknown function. The protein is also approximately 25% identical to the Drosophila protein suppressor of hairy wing, which is a leucine zipper protein that represses the function of transcriptional enhancers of the gypsy retrotransposon. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
Product Categories/Family for anti-ZNF280B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61kDa
NCBI Official Full Name
zinc finger protein 280B
NCBI Official Synonym Full Names
zinc finger protein 280B
NCBI Official Symbol
ZNF280B
NCBI Official Synonym Symbols
SUHW2; ZNF279; ZNF632; 5'OY11.1; D87009.C22.3
NCBI Protein Information
zinc finger protein 280B
UniProt Protein Name
Zinc finger protein 280B
Protein Family
UniProt Gene Name
ZNF280B
UniProt Synonym Gene Names
SUHW2; ZNF279; ZNF632
UniProt Entry Name
Z280B_HUMAN
NCBI Description
The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]
Uniprot Description
Function: May function as a transcription factor.
Subcellular location: Nucleus
Potential.
Sequence similarities: Contains 4 C2H2-type zinc fingers.
Sequence caution: The sequence BAA20005.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on ZNF280B
Similar Products
Product Notes
The ZNF280B znf280b (Catalog #AAA3204844) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF280B antibody - C-terminal region reacts with Cow, Dog, Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF280B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ZNF280B znf280b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PPETKVTIQV SLEPLQPGSV DVASITVSTS DSEPSLPRSK SKISKKSH. It is sometimes possible for the material contained within the vial of "ZNF280B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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