Western Blot (WB)
(ZNF280B Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the ZNF280B antibody detected the ZNF280B protein (arrow).)
Rabbit anti-Human ZNF280B Polyclonal Antibody | anti-ZNF280B antibody
ZNF280B Antibody (N-term)
Gene Names
ZNF280B; SUHW2; ZNF279; ZNF632; 5'OY11.1; D87009.C22.3
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ZNF280B; Polyclonal Antibody; ZNF280B Antibody (N-term); Zinc finger protein 280B; 5'OY111; Suppressor of hairy wing homolog 2; Zinc finger protein 279; Zinc finger protein 632; SUHW2; ZNF279; ZNF632; anti-ZNF280B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ZNF280B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human ZNF280B.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.45 (varies by lot)
Sequence Positions
60-89
Sequence Length
543
Applicable Applications for anti-ZNF280B antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(ZNF280B Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the ZNF280B antibody detected the ZNF280B protein (arrow).)
Western Blot (WB)
(ZNF280B Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the ZNF280B antibody detected the ZNF280B protein (arrow).)
Related Product Information for anti-ZNF280B antibody
This gene was identified by homology to other species. Its
encoded protein is approximately 78-88% identical to a predicted
sheep protein of unknown function. The protein is also
approximately 25% identical to the Drosophila protein suppressor of
hairy wing, which is a leucine zipper protein that represses the
function of transcriptional enhancers of the gypsy retrotransposon.
encoded protein is approximately 78-88% identical to a predicted
sheep protein of unknown function. The protein is also
approximately 25% identical to the Drosophila protein suppressor of
hairy wing, which is a leucine zipper protein that represses the
function of transcriptional enhancers of the gypsy retrotransposon.
References
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Dunham, I., et al. Nature 402(6761):489-495(1999)
Kawasaki, K., et al. Genome Res. 7(3):250-261(1997)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Dunham, I., et al. Nature 402(6761):489-495(1999)
Kawasaki, K., et al. Genome Res. 7(3):250-261(1997)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61584
NCBI Official Full Name
zinc finger protein 280B
NCBI Official Synonym Full Names
zinc finger protein 280B
NCBI Official Symbol
ZNF280B
NCBI Official Synonym Symbols
SUHW2; ZNF279; ZNF632; 5'OY11.1; D87009.C22.3
NCBI Protein Information
zinc finger protein 280B
UniProt Protein Name
Zinc finger protein 280B
Protein Family
UniProt Gene Name
ZNF280B
UniProt Synonym Gene Names
SUHW2; ZNF279; ZNF632
UniProt Entry Name
Z280B_HUMAN
NCBI Description
The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]
Uniprot Description
ZNF280B: May function as a transcription factor.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 22q11.22
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Research Articles on ZNF280B
Similar Products
Product Notes
The ZNF280B znf280b (Catalog #AAA9214446) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 60-89. The ZNF280B Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF280B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ZNF280B znf280b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF280B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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