Rabbit anti-Human ZBED1 Polyclonal Antibody | anti-ZBED1 antibody

ZBED1 (Zinc Finger BED Domain-containing Protein 1, Putative Ac-like Transposable Element, ALTE, dREF Homolog, DREF, KIAA0785, TRAMP) (PE)

Cat. Num. AAA6398908

• Gene Names: ZBED1; ALTE; DREF; TRAMP; hDREF
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ZBED1; Polyclonal Antibody; ZBED1 (Zinc Finger BED Domain-containing Protein 1; Putative Ac-like Transposable Element; ALTE; dREF Homolog; DREF; KIAA0785; TRAMP) (PE); anti-ZBED1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ZBED1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-ZBED1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human ZBED1, aa1-694 (NP_004720.1)
• Immunogen Sequence: MENKSLESSQTDLKLVAHPRAKSKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKPESSQQPGQDALAVKAGHGYDSKKQQELTAAVLGLICEGLYPASIVDEPTFKVLLKTADPRYELPSRKYISTKAIPEKYGAVREVILKELAEATWCGISTDMWRSENQNRAYVTLAAHFLGLGAPNCLSMGSRCLKTFEVPEENTAETITRVLYEVFIEWGISAKVFGATTNYGKDIVKACSLLDVAVHMPCLGHTFNAGIQQAFQLPKLGALLSRCRKLVEYFQQSAVAMYMLYEKQKQQNVAHCMLVSNRVSWWGSTLAMLQRLKEQQFVIAGVLVEDSNNHHLMLEASEWATIEGLVELLQPFKQVAEMLSASRYPTISMVKPLLHMLLNTTLNIKETDSKELSMAKEVIAKELSKTYQETPEIDMFLNVATFLDPRYKRLPFLSAFERQQVENRVVEEAKGLLDKVKDGGYRPAEDKIFPVPEEPPVKKLMRTSTPPPASVINNMLAEIFCQTGGVEDQEEWHAQVVEELSNFKSQKVLGLNEDPLKWWSDRLALFPLLPKVLQKYWCVTATRVAPERLFGSAANVVSAKRNRLAPAHVDEQVFLYENARSGAEAEPEDQDEGEWGLDQEQVFSLGDGVSGGFFGIRDSSFL
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ZBED1 rabbit polyclonal antibody. Western Blot analysis of ZBED1 expression in human colon.)

Western Blot (WB)

(Western Blot analysis of ZBED1 expression in transfected 293T cell line by ZBED1 polyclonal antibody. Lane 1: ZBED1 transfected lysate (78.2kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-ZBED1 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 15929151
• NCBI GeneID: 9189
• NCBI Accession #: AAH15030
• NCBI GenBank Nucleotide #: NM_004729.3
• UniProt Accession #: O96006; Q96BY4
• Molecular Weight: 78,156 Da
• NCBI Official Full Name: ZBED1 protein
• NCBI Official Synonym Full Names: zinc finger, BED-type containing 1
• NCBI Official Symbol: ZBED1
• NCBI Official Synonym Symbols: ALTE; DREF; TRAMP; hDREF
• NCBI Protein Information: zinc finger BED domain-containing protein 1; dREF homolog; Ac-like transposable element; DNA replication-related element binding factor; BED-type zinc finger domain-containing protein 1
• UniProt Protein Name: Zinc finger BED domain-containing protein 1
• Protein Family: Zinc finger BED domain-containing protein
• UniProt Gene Name: ZBED1
• UniProt Synonym Gene Names: ALTE; DREF; KIAA0785; TRAMP
• UniProt Entry Name: ZBED1_HUMAN

NCBI Description

This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]

Uniprot Description

ZBED1: Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: Xp22.33;Yp11

Cellular Component: nuclear chromosome

Molecular Function: protein dimerization activity; DNA binding; metal ion binding; transposase activity

Biological Process: metabolic process