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Western Blot (WB) (Western blot analysis of ZAP70 (pY315) expression in Jurkat H2O2-treated (A); HeLa H2O2-treated (B); Ramos lambda phosphatase-treated (C); mouse kidney (D); rat kidney (E) whole cell lysates.)

Rabbit ZAP70 Polyclonal Antibody | anti-ZAP70 antibody

ZAP70 Antibody

Gene Names
ZAP70; SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
ZAP70; Polyclonal Antibody; ZAP70 Antibody; Purified Polyclonal ZAP70 Antibody; Polyclonal ZAP70 antibody; Anti-ZAP70 antibody; SRK antibody; Tyrosine-protein kinase ZAP-70 antibody; 70 kDa zeta-chain associated protein antibody; Syk-related tyrosine kinase antibody; anti-ZAP70 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of ZAP70 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
493
Applicable Applications for anti-ZAP70 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
ZAP70 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ZAP70 as the immunogen
Cross-Reactivity
Mouse, Rat, Bovine, Chicken, Monkey, Pig, Rabbit
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of ZAP70 (pY315) expression in Jurkat H2O2-treated (A); HeLa H2O2-treated (B); Ramos lambda phosphatase-treated (C); mouse kidney (D); rat kidney (E) whole cell lysates.)

Western Blot (WB) (Western blot analysis of ZAP70 (pY315) expression in Jurkat H2O2-treated (A); HeLa H2O2-treated (B); Ramos lambda phosphatase-treated (C); mouse kidney (D); rat kidney (E) whole cell lysates.)
Related Product Information for anti-ZAP70 antibody
ZAP70 is a cytoplasmic protein tyrosine kinase that plays a critical role in the events involved in initiating T-cell responses by the antigen receptor.
Product Categories/Family for anti-ZAP70 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
ZAP70 protein
NCBI Official Synonym Full Names
zeta chain of T cell receptor associated protein kinase 70
NCBI Official Symbol
ZAP70
NCBI Official Synonym Symbols
SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
NCBI Protein Information
tyrosine-protein kinase ZAP-70
Protein Family

NCBI Description

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Research Articles on ZAP70

Similar Products

Product Notes

The ZAP70 (Catalog #AAA5315184) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ZAP70 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the ZAP70 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZAP70, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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