Immunofluorescence (IF)
(IF / Cell Line: HeLa)
Rabbit WRS (Tryptophanyl-tRNA Synthetase) Polyclonal Antibody | anti-WRS antibody
WRS (Tryptophanyl-tRNA Synthetase)
Gene Names
SCO3334; SCE68.32; SCE7.01; trpS
Reactivity
Human, Mouse. Other species are not tested.
Applications
Western Blot, Immunofluorescence
Synonyms
WRS (Tryptophanyl-tRNA Synthetase); Polyclonal Antibody; Tryptophanyl-tRNA Synthetase pAb; WARS; IFI53; IFP53; TrpRS; anti-WRS antibody
Host
Rabbit
Reactivity
Human, Mouse. Other species are not tested.
Clonality
Polyclonal
Specificity
This antibody reacts specifically with 53kDa tryptophanyl tRNA synthetase protein.
Form/Format
Serum containing 0.05% sodium azide for preservative.
Sequence Length
336
Applicable Applications for anti-WRS antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:5000
Immunogen
Native full length human recombinant WRS.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at 4 degree C or -20 degree C.
Immunofluorescence (IF)
(IF / Cell Line: HeLa)
Immunofluorescence (IF)
(IF / Cell Line: HeLa)
Western Blot (WB)
(WB / Cell line: HEK293)
Western Blot (WB)
(WB / Cell line: HEK293)
Western Blot (WB)
(WB / Cell line: HeLa)
Western Blot (WB)
(WB / Cell line: HeLa)
Related Product Information for anti-WRS antibody
Tryptophanyl-tRNA synthetase (WRS) basically catalyzes the ligation of tryptophan with tryptophanyl-tRNA. WRS is overexpressed by IFNg and secreted to inhibit the vascular angiogenesis.
References
1. Trp-tRNAsynthetase bridges DNA-PKcs to PARP-1 to link IFN-gamma and p53 signaling. Mathew Sajish et al., NATURE CHEMICAL BIOLOGY, Vol.8, 547-554, 2012. 2. Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster. Gye Won Han et al., Acta Cryst., F66, 1326-1334, 201. 3. Structure of human tryptophanyl-tRNA synthetase in complex with tRNATrp reveals the molecular basis of tRNA recognition and specificity. Ning Shen et al., Nucleic Acids Research, Vol.34, No.11, 2006. 4. Human tryptophanyl-tRNA synthetase is switched to a tRNA-dependent mode for tryptophan activation by mutations at V85 and I311. Li-Tao Guo et al., Nucleic Acids Research, Vol.35, No.17, 2007. 5. A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase. Yoshiaki Kise et al., Nature Structural & Molecular Biology, Vol.11, 149-156, 2004. 6. Interconversion of ATP Binding and Conformational Free Energies by Tryptophanyl-tRNA Synthetase: Structures of ATP Bound to Open and Closed, PreTransition-state Conformations. Pascal Retailleau et al., J. Mol. Biol., Vol.325, 39-63, 2003. 7. A human aminoacyl-tRNA synthetase as a regulator of angiogenesis. Keisuke Wakasugi et al., PNAS, Vol. 99(1), 173-177, 2002.
NCBI and Uniprot Product Information
Similar Products
Product Notes
The WRS (Catalog #AAA490303) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WRS (Tryptophanyl-tRNA Synthetase) reacts with Human, Mouse. Other species are not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's WRS (Tryptophanyl-tRNA Synthetase) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:5000. Researchers should empirically determine the suitability of the WRS for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WRS (Tryptophanyl-tRNA Synthetase), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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