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WRS (Tryptophanyl-tRNA Synthetase) Recombinant Protein | WRS recombinant protein
WRS (Tryptophanyl-tRNA Synthetase)
Gene Names
SCO3334; SCE68.32; SCE7.01; trpS
Purity
97.1%Multi-Step Chromatography
Synonyms
WRS (Tryptophanyl-tRNA Synthetase); Tryptophanyl-tRNA Synthetase; IFI53; IFP53; WRS recombinant protein
Host
E Coli
Purity/Purification
97.1%
Multi-Step Chromatography
Multi-Step Chromatography
Form/Format
Phosphate buffered saline, pH 7.4.
Concentration
0.67 mg/ml (varies by lot)
Sequence Positions
471aa
Sequence Length
336
Source
Human
Conjugation/Tag
Conjugated, His tag
Preparation and Storage
Store at -70 degree C.
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SDS-Page
Related Product Information for WRS recombinant protein
Tryptophanyl-tRNA synthetase (WRS) basically catalyzes the ligation of tryptophan with tryptophanyl-tRNA. WRS is overexpressed by IFNg and secreted to inhibit the vascular angiogenesis. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. TryptophanyltRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
References
1. Trp-tRNAsynthetase bridges DNA-PKcs to PARP-1 to link IFN-? and p53 signaling. Mathew Sajish et al., NATURE CHEMICAL BIOLOGY, Vol.8, 547-554, 2012. 2. Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster. Gye Won Han et al., Acta Cryst., F66, 1326-1334, 2010. 3. Structure of human tryptophanyl-tRNA synthetase in complex with tRNATrp reveals the molecular basis of tRNA recognition and specificity. Ning Shen et al., Nucleic Acids Research, Vol.34, No.11, 2006.
NCBI and Uniprot Product Information
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Product Notes
The WRS (Catalog #AAA490322) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 471aa. It is sometimes possible for the material contained within the vial of "WRS (Tryptophanyl-tRNA Synthetase), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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