Rabbit anti-Human WDR12 Polyclonal Antibody | anti-WDR12 antibody

WDR12, ID (WDR12, Ribosome biogenesis protein WDR12, WD repeat-containing protein 12) (AP)

Cat. Num. AAA6363093

• Gene Names: WDR12; YTM1
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: WDR12; Polyclonal Antibody; ID (WDR12; Ribosome biogenesis protein WDR12; WD repeat-containing protein 12) (AP); WD repeat-containing protein 12; anti-WDR12 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-WDR12 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: WDR12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-239 amino acids from the Central region of human WDR12.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(WDR12 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the WDR12 antibody detected the WDR12 protein (arrow).)

Immunohistochemistry (IHC)

(WDR12 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WDR12 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-WDR12 antibody

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.

Product Categories/Family for anti-WDR12 antibody

Antibodies; WD Repeat Proteins

References

Kathiresan, S., et al. Nat. Genet. 41(3):334-341(2009). Rohrmoser, M., et al. Mol. Cell. Biol. 27(10):3682-3694(2007). Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006). Grimm, T., et al. Nucleic Acids Res. 34(10):3030-3043(2006). Holzel, M., et al. J. Cell Biol. 170(3):367-378(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 217330644
• NCBI GeneID: 55759
• NCBI Accession #: NP_060726.3
• NCBI GenBank Nucleotide #: NM_018256.3
• UniProt Accession #: Q9GZL7; Q96HU0; Q9NV80; Q9NYI8; B3KPA9
• Molecular Weight: 47,708 Da
• NCBI Official Full Name: ribosome biogenesis protein WDR12
• NCBI Official Synonym Full Names: WD repeat domain 12
• NCBI Official Symbol: WDR12
• NCBI Official Synonym Symbols: YTM1
• NCBI Protein Information: ribosome biogenesis protein WDR12; WD repeat-containing protein 12
• UniProt Protein Name: Ribosome biogenesis protein WDR12
• Protein Family: Ribosome biogenesis protein
• UniProt Gene Name: WDR12
• UniProt Entry Name: WDR12_HUMAN