anti-Mouse, Rat Tyrosine Hydroxylase Antibody | anti-TYH antibody

Tyrosine Hydroxylase (Phospho-Ser8) Antibody

Cat. Num. AAA858805

• Reactivity: Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
• Synonyms: Tyrosine Hydroxylase; Tyrosine Hydroxylase (Phospho-Ser8) Antibody; EC 1.14.16.2; TH isoform 3; TH isoform a; TH-4; TY3H; Tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase; tyrosine hydroxylase; anti-TYH antibody

• Reactivity: Mouse, Rat
• Specificity: Tyrosine Hydroxylase (Phospho-Ser8) antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 8.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 498

• Applicable Applications for anti-TYH antibody: Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; IHC: 1:50~1:100; ELISA: 1:1000
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 8 (A-P-SP-P-Q).
• All Sites: Mouse: Ser8; Rat: Ser8
• Preparation and Storage: Store at-20 degree C for 1 year.

Testing Data

(P-peptide-+)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human brain tissue using Tyrosine Hydroxylase (Phospho-Ser8) antibody. Western blot analysis of extracts from HepG2 cells, treated with Anisomycin (25ug/ml, 30mins), using Tyrosine Hydroxylase (Phospho-Ser8) antibody.)

Product Categories/Family for anti-TYH antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

References

Marco Cosentino, Blood, Jan 2007; 109: 632-642. ZG Xue, J. Neurosci., Mar 1988; 8: 806. L Iacovitti, J. Neurosci., Apr 1987; 7: 1264. DM Kuhn, J. Biol. Chem., Apr 1990; 265: 5780-5786.

NCBI and Uniprot Product Information

• NCBI GI #: 6678337
• NCBI GeneID: 21823
• NCBI Accession #: NP_033403.1
• NCBI GenBank Nucleotide #: NM_009377.1
• UniProt Accession #: P24529
• Molecular Weight: 55,993 Da
• NCBI Official Full Name: tyrosine 3-monooxygenase
• NCBI Official Synonym Full Names: tyrosine hydroxylase
• NCBI Official Symbol: Th
• NCBI Protein Information: tyrosine 3-monooxygenase
• UniProt Protein Name: Tyrosine 3-monooxygenase
• UniProt Gene Name: Th
• UniProt Synonym Gene Names: TH

Uniprot Description

Plays an important role in the physiology of adrenergic neurons.