Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Mammary, Cancer Tissue)
Rabbit Vinculin Polyclonal Antibody | anti-VCL antibody
Vinculin Antibody
Gene Names
VCL; MV; MVCL; CMD1W; CMH15; HEL114
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
Vinculin; Polyclonal Antibody; Vinculin Antibody; Affinity Purified Mouse Polyclonal Vinculin Antibody; Polyclonal Vinculin antibody; Anti-Vinculin antibody; anti-VCL antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
130
Applicable Applications for anti-VCL antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Immunogen
Vinculin antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human VCL, identical to the related rat and Rabbit sequences, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Mammary, Cancer Tissue)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Mammary, Cancer Tissue)
Related Product Information for anti-VCL antibody
In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is associated with focal adhesion and adherens junctions, which are complexes that nucleates actin filaments and crosslinkers between the external medium, plasma membrane, and actin cytoskeleton.
Product Categories/Family for anti-VCL antibody
NCBI and Uniprot Product Information
NCBI Description
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Research Articles on VCL
Similar Products
Product Notes
The VCL (Catalog #AAA5313066) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Vinculin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the VCL for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vinculin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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