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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TEP1 antibody.)

anti-Human TEP1 Antibody | anti-TEP1 antibody

TEP1 Antibody

Gene Names
TEP1; TP1; TLP1; p240; TROVE1; VAULT2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TEP1; TEP1 Antibody; Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog; anti-TEP1 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
TEP1 antibody detects endogenous levels of total TEP1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
2627
Applicable Applications for anti-TEP1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TEP1.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TEP1 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TEP1 antibody.)
References
Harrington L., Science 275:973-977(1997). Harrington L., Genes Dev. 11:3109-3115(1997). Kickhoefer V.A., J. Biol. Chem. 274:32712-32717(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
289,578 Da
NCBI Official Full Name
telomerase protein component 1 isoform 1
NCBI Official Synonym Full Names
telomerase associated protein 1
NCBI Official Symbol
TEP1
NCBI Official Synonym Symbols
TP1; TLP1; p240; TROVE1; VAULT2
NCBI Protein Information
telomerase protein component 1
UniProt Protein Name
Telomerase protein component 1
UniProt Gene Name
TEP1
UniProt Synonym Gene Names
TLP1; TP1; Telomerase protein 1

NCBI Description

This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Uniprot Description

Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC ().

Research Articles on TEP1

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Product Notes

The TEP1 tep1 (Catalog #AAA851392) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TEP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TEP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the TEP1 tep1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TEP1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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