Rabbit FMNL2 Polyclonal Antibody | anti-FMNL2 antibody

Rabbit Polyclonal (IgG) to Human FMNL2

Cat. Num. AAA241708

• Gene Names: FMNL2; FHOD2
• Reactivity: Bovine, Chimpanzee, Human, Monkey, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Protein G Purified
• Synonyms: FMNL2; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human FMNL2; Anti-FMNL2 Antibody IHC-plus; Formin-like protein 2; FHOD2; KIAA1902; Formin-like 2; Human FMNL2; anti-FMNL2 antibody

• Host: Rabbit
• Reactivity: Bovine, Chimpanzee, Human, Monkey, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: A portion of amino acid 1-50 of human Formin-like protein 2
• Purity/Purification: Protein G Purified
• Form/Format: PBS, 0.05% BSA, 0.05% sodium azide.
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 1092

• Applicable Applications for anti-FMNL2 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 - 10 ug/ml), WB (1 - 3 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic peptide from human FMNL2.
• Immunogen Type: Synthetic peptide
• Immunogen: FMNL2 antibody was raised against synthetic peptide from human FMNL2.
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-FMNL2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of Formin-like protein 2 in whole mouse embryo body tissue lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 2 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 52485606
• NCBI GeneID: 114793
• NCBI Accession #: NP_443137.2
• NCBI GenBank Nucleotide #: NM_052905.3
• UniProt Accession #: Q96PY5; Q14CC9; Q4ZG52; Q8N3E0; B2RZH5
• Molecular Weight: 124,107 Da
• NCBI Official Full Name: formin-like protein 2
• NCBI Official Synonym Full Names: formin-like 2
• NCBI Official Symbol: FMNL2
• NCBI Official Synonym Symbols: FHOD2
• NCBI Protein Information: formin-like protein 2; formin homology 2 domain containing 2; formin homology 2 domain-containing protein 2
• UniProt Protein Name: Formin-like protein 2
• UniProt Gene Name: FMNL2
• UniProt Synonym Gene Names: FHOD2; KIAA1902
• UniProt Entry Name: FMNL2_HUMAN

NCBI Description

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]

Uniprot Description

FMNL2: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics. Belongs to the formin homology family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 2q23.3

Cellular Component: cytoplasm

Molecular Function: Rho GTPase binding; actin binding

Biological Process: regulation of cell morphogenesis; cytoskeleton organization and biogenesis; cortical actin cytoskeleton organization and biogenesis