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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using VEZT Polyclonal Antibody at dilution of 1:30(×200))

Rabbit anti-Human VEZT Polyclonal Antibody | anti-VEZT antibody

VEZT Polyclonal Antibody

Gene Names
VEZT; VEZATIN
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
VEZT; Polyclonal Antibody; VEZT Polyclonal Antibody; Vezatin; anti-VEZT antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.5mg/mL (varies by lot)
Sequence Length
779
Applicable Applications for anti-VEZT antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:20-1:100
ELISA: 1:5000-1:10000
Immunogen
Synthetic peptide of human VEZT
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using VEZT Polyclonal Antibody at dilution of 1:30(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using VEZT Polyclonal Antibody at dilution of 1:30(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using VEZT Polyclonal Antibody at dilution of 1:30(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human tonsil tissue using VEZT Polyclonal Antibody at dilution of 1:30(×200))
Related Product Information for anti-VEZT antibody
This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-VEZT antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
vezatin isoform b
NCBI Official Synonym Full Names
vezatin, adherens junctions transmembrane protein
NCBI Official Symbol
VEZT
NCBI Official Synonym Symbols
VEZATIN
NCBI Protein Information
vezatin
UniProt Protein Name
Vezatin
Protein Family
UniProt Gene Name
VEZT
UniProt Entry Name
VEZA_HUMAN

NCBI Description

This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

Uniprot Description

VEZATIN: Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. In case of Listeria infection, promotes bacterial internalization by participating in myosin VIIa recruitment to the entry site. Belongs to the vezatin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q22

Cellular Component: nucleoplasm; adherens junction; cytoplasm; acrosome; plasma membrane; integral to membrane

Molecular Function: myosin binding

Biological Process: cell-cell adhesion; chordate embryonic development

Research Articles on VEZT

Similar Products

Product Notes

The VEZT vezt (Catalog #AAA2563468) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VEZT Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VEZT can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:20-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the VEZT vezt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VEZT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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