Rabbit anti-Human VCX3A Polyclonal Antibody | anti-VCX3A antibody

VCX3A, NT (VCX3A, VCX3, VCX8R, VCXA, Variable charge X-linked protein 3, Variable charge protein on X with eight repeats, Variably charged protein X-A) (AP)

Cat. Num. AAA6362378

• Gene Names: VCX3A; VCX3; VCXA; VCX-A; VCX8R; VCX-8r
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: VCX3A; Polyclonal Antibody; NT (VCX3A; VCX3; VCX8R; VCXA; Variable charge X-linked protein 3; Variable charge protein on X with eight repeats; Variably charged protein X-A) (AP); Variably charged protein X-A; anti-VCX3A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-VCX3A antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: VCX3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human VCX3A.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(VCX3A Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the VCX3A antibody detected the VCX3A protein (arrow).)

Related Product Information for anti-VCX3A antibody

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq].

Product Categories/Family for anti-VCX3A antibody

Antibodies; RNA Processing

References

Jiao, X., et al. J. Neurosci. 29(40):12419-12427(2009). Cuevas-Covarrubias, S.A., et al. Br. J. Dermatol. 158(3):483-486(2008). Jiao, X., et al. Mol. Cell 24(5):713-722(2006). Fukami, M., et al. Am. J. Hum. Genet. 67(3):563-573(2000). Lahn, B.T., et al. Hum. Mol. Genet. 9(2):311-319(2000).

NCBI and Uniprot Product Information

• NCBI GI #: 48762947
• NCBI GeneID: 51481
• NCBI Accession #: NP_057463.2
• NCBI GenBank Nucleotide #: NM_016379.3
• UniProt Accession #: Q9NNX9; Q9P0H4
• Molecular Weight: 20,020 Da
• NCBI Official Full Name: variable charge X-linked protein 3
• NCBI Official Synonym Full Names: variable charge, X-linked 3A
• NCBI Official Symbol: VCX3A
• NCBI Official Synonym Symbols: VCX3; VCXA; VCX-A; VCX8R; VCX-8r
• NCBI Protein Information: variable charge X-linked protein 3; variably charged X-A; variably charged protein X-A; variable charge protein on X with eight repeats
• UniProt Protein Name: Variable charge X-linked protein 3
• Protein Family: Variable charge X-linked protein
• UniProt Gene Name: VCX3A
• UniProt Synonym Gene Names: VCX3; VCX8R; VCXA; VCX-8r; VCX-A
• UniProt Entry Name: VCX3_HUMAN

NCBI Description

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]

Uniprot Description

VCX3A: May mediate a process in spermatogenesis or may play a role in sex ratio distortion. Belongs to the VCX/VCY family.

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: nucleolus; nucleus

Biological Process: brain development